… been well described in the peripheral nervous system (PNS). … In vivo, caspase-3 KO mice
display a lack of attention and … ” effects of caspase-3 activation suggests that nerve cells may be …

… toxins also affect the nervous system, and the severe depression, lack of … Both C2 toxin and
C3 exoenzyme are ADP- … diffuses via vascular channels or peripheral nerve trunks. The toxin …

… The Bowman's membrane lacks regenerative capacity, resulting in the … However, the
technology for in vitro cultivation of corneal … Lentiviral vector‐mediated expression of exoenzyme …

… -ribosylating toxin, and an C3 exoenzyme which has led to BoNT… For some years, an in vitro
replacement for the mouse … structurally similar to the toxin but lacking the zinc-binding motif …

… Accordingly, lack of Smad3 has been associated to reduced secretion of ECM … in vivo
PVR mouse model [133]. Interestingly, the upstream blockade of RhoA by C3 exoenzyme or …

… Afterward, lead compounds are tested in vivo to identify drug … mimic the function of C3
exoenzyme residues Asn98, Val96 and … the electronic effects of the substituents had little impact …

… not affect SMNs isolated from task1 −/− embryos (SMNs task1−/− ), it lowered IME and increased
TASK-dependent changes in SMNs wt and SMNs task3−/− (lacking … estimated in vitro by …

… into odontoblasts in vivo. However, they were unable to regenerate complete dentin–pulp-…
Although they observed lack of spontaneous excitatory/inhibitory postsynaptic action potential. …

… responses, the lack of functional improvement associated with … The downregulation of
Vcam1 and Cdh15 in SRCs C3 … terms of regenerative capacity in mice; however, their effect on …

… 304308 RhoA inhibition using C3 exoenzyme and … 365 But what is lacking is the
understanding of the effects of … promotes axon regeneration in the rat optic nerve in vivo and …