… lacking p75NTR, it has been found to have a reduced axonal … RGM is found in vivo in structures
that direct axons by … RhoA, such as using C3 exoenzyme or overexpression of dominant-…

… axons. In contrast to the central nervous system, the peripheral nervous system lacks the
blood… Here we describe an easy in vitro assay to culture postnatal spinal cord organotypic slices …

… after peripheral nerve cut or sham operation and effect of inhibition of AMC with BDM in vivo.
… Uptake of clostridium botulinum C3 exoenzyme into intact HT22 and J774A.1 cells. Toxins (…

… toxin C3 exoenyzme after spinal cord injury enables axon … because RhoANesKO neurons
lacked such an increase in … promote axon regeneration after spinal cord injury (SCI) in vivo…

… such as arterial hypotension, lack of sweating, and alterations … OECs have shown several
beneficial effects in in vitro and in … Rho antagonists such as C3-exoenzyme, fasudil, Y-27532, …

… Recovery from TBI can be challenging due to a lack of effective … the inhibitory effects of
these molecules on axon outgrowth … The exoenzyme C3 transferase is a RhoA antagonist that …

… Exoenzyme C3 transferase is an enzyme found in Clostridium … effect of C3 transferase in
promoting axonal regeneration … neuroprotective effects in both in vitro and in vivo studies of TBI…

… and preventing RGC cell death in vitro and in vivo [11, 12]. These … expression of scAAV2-C3
(exoenzyme C3 transferase), … when transplanted into mouse eyes lacking original RGCs and …

… inflammatory response, the lack of neurotrophic factors, the … collapse, thus Rho antagonists
(C3-exoenzyme, fasudil, Y-27632… spinal cord injury comes in two forms: in vivo and ex vivo. In …

… microglia activation and peripheral macrophage infiltration occur … as a biomarker of SCI may
lack specificity, it would be … of exosomes in vivo, thereby enhancing the effects of exosomes …