[PDF][PDF] Microglia dysfunction caused by the loss of rhoa disrupts neuronal physiology and leads to neurodegeneration

R Socodato, CC Portugal, T Canedo, A Rodrigues… - Cell Reports, 2020 - cell.com
… We then evaluated the impact of microglia-dependent neuro… Because blocking Src activity
in microglia lacking Rhoa abro… to TNF, our in vitro data demonstrated that TNF signaling was …

Improving chemotherapeutic regimens by mitigating hearing loss as a limiting side-effect and examining transition metal ions as a ligand for zebrafish Tlr4

A Fox - 2023 - era.library.ualberta.ca
vivo. By creating a heterologous cell system using zebrafish Tlr4, we extended these findings
… Bhavsar lab was responsible for the in vitro cell culture work. Christie Li generated gRNA …

[PDF][PDF] Ocular Gene Therapy

M Naser, MM Nasr, LH Shehata - 2022 - researchgate.net
… surface have been offered in vitro or the utilization of animal … are its biodegradability and
lack of toxicity. Another NP … -mediated switch of exoenzyme C3 transferase gene, which …

Sensory regulated Wnt production from neurons helps make organ development robust to environmental changes in C. elegans

K Modzelewska, L Brown, J Culotti… - Development, 2020 - journals.biologists.com
… did not affect the 3 fate frequency of P4.p, and effects on P3.p … C3 exoenzyme from Clostridium
botulinum, which specifically ADP ribosylates and inactivates RhoA, B and C, and has no

New approaches to study the architecture and dynamics of the sealing zone in osteoclasts

M Portes - 2019 - laas.hal.science
renewal of bone matrix. Indeed, slight variations from this balance can have dramatic effects
on … Matching resorption patterns generated by OCs in vitro and in vivo. (a) Pits (left) and …

[PDF][PDF] Bacterial biofilm interactions with human immune cells

K Lee - 2022 - core.ac.uk
… aureus (SH1000), into our in vitro biofilm model which … due to excessive salt and oils as well
as a lack of nutrients (5, 6). It is … and C4b combine to form a C3-convertase (C4b2b complex). …

[PDF][PDF] CHARACTERIZING A ROLE FOR NOS1AP IN CELLULAR MECHANOTRANSDUCTION

I Shahin - 2021 - dalspace.library.dal.ca
In a screen for proteins that interact with the phosphotyrosine binding (PTB) domain of NOS1AP
we identified the β-integrin family of proteins. Fibronectin stimulated mouse embryonic …

[HTML][HTML] Control of actin polymerization via reactive oxygen species generation using light or radiation

T Ishimoto, H Mori - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
… However, if you want to analyze the effects of actin polymerization on cellular functions, you
should make sure that the method you use does not have genotoxicity. So far, there are no …

A Tale of Two Transfers: POMGNT2 Specificity in Protein O-Mannosylation and Problem Solving in Undergraduate Biochemistry

SM Halmo - 2020 - search.proquest.com
… In vitro, POMGNT2 displays significant primary amino acid … that investigates the comparative
impacts of different pedagogies, … -1-P to the C3 position of GalNAc through a phosphodiester …

[PDF][PDF] Analýza buněčné polarizace pomocí pokročilých mikroskopických metod

Š ČADA - is.muni.cz
peripheral SMAC PTEN … Ras-related C3 botulinum toxin substrate 1 or 2 RAP1 … of Wnt/PCP
and Wnt/Ca2+ pathways together but will distinguish their effect in cases where the individual …