… careful examination of the complement abnormality. Differential … complement attack influences
the function of the glomeruli. … disease (DDD) and C3 glomerulonephritis (C3GN) based on …

… Patients tested for complement abnormalities can have a variety of complement factor genetic
… acute PIGN from C3G in those difficult cases with overlapping clinicopathologic features. …

… In PIGN, complement abnormalities are transient and C3 … as C3 glomerulopathy is warranted
if C3 levels remain … to human C3 glomerulopathy, including C3 glomerular deposition in the …

… C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of the
alternative complement pathway in plasma and the glomerular … abnormalities in complement …

… glomerulus, control of the complement pathway is important in maintaining neutrality. Glycocalyx
is a major component of the glomerular … to screen for complement abnormality is CH50, …

… glomerular complement deposits as well as in glomerular lesions in DDD. At variance with
findings in C3GN and DDD, terminal complement … in IC-MPGN glomerular deposits [60] which …

… Membranoproliferative GN (MPGN) is a pattern of glomerular injury … C3 glomerulopathy
on the basis of relative complement and Ig staining on biopsy specimens. C3 glomerulopathy …

… regulatory factors are highly implicated in C3 glomerulopathy (which encompasses C3 …
of abnormal complement regulation and activation as the source of glomerular disease. …

… in clinicopathologic features2); (ii) … glomerular C3 deposition in patients with C3 glomerulopathy
is at least 2level more intensely stained in IF preparations than are other complement …

… However, updated definitions allow for glomerular deposition of other complement factors
or … The overlapping clinicopathological features of C3G and IRGN, mainly the PIGN pattern, …