[HTML][HTML] Duality of B cell-CXCL13 axis in tumor immunology
AJ Rubio, T Porter, X Zhong - Frontiers in Immunology, 2020 - frontiersin.org
… helper T cells and is essential for naive B cell homing and organization … immunity to the
peritoneal cavity (70). This is evidenced in CXCL13-deficient mice which have reduced B1 B cell …
peritoneal cavity (70). This is evidenced in CXCL13-deficient mice which have reduced B1 B cell …
[HTML][HTML] CXCL13 in cancer and other diseases: biological functions, clinical significance, and therapeutic opportunities
SH Gao, SZ Liu, GZ Wang, GB Zhou - Life, 2021 - mdpi.com
… cells in SLOs are B-2 cells, CXCL13 also recruits B-1 cells into the body cavity, which triggers
early immune … B cells homing into the TME via the CXCL13/CXCR5 axis include pro-tumor …
early immune … B cells homing into the TME via the CXCL13/CXCR5 axis include pro-tumor …
[HTML][HTML] Role of the CXCL13/CXCR5 axis in autoimmune diseases
Z Pan, T Zhu, Y Liu, N Zhang - Frontiers in Immunology, 2022 - frontiersin.org
… In addition, CXCL13 and CXCR5 are required for B-cell homing in … through attracting B1 cell
toward the body cavity. In … Anti-CXCL13 antibody reduced B cells in the lymphoid infiltration, …
toward the body cavity. In … Anti-CXCL13 antibody reduced B cells in the lymphoid infiltration, …
CXCL13/CXCR5 signaling axis in cancer
… IgM antibodies for early protection from infections [41,48]. CXCL13/CXCR5-derived B-1 B
cells homing to body cavities is thus … of an early B cell-mediated innate immune response [41]. …
cells homing to body cavities is thus … of an early B cell-mediated innate immune response [41]. …
CXCL13 signaling in the tumor microenvironment
… by regulating noncancerous cells, particularly the immune cells, … For instance, CXCL13-CXCR5-derived
homing of B-1 B cells… [41]—to body cavities plays a dominant role in balanced …
homing of B-1 B cells… [41]—to body cavities plays a dominant role in balanced …
[HTML][HTML] PD-1+ CXCR5− CD4+ Th-CXCL13 cell subset drives B cells into tertiary lymphoid structures of nasopharyngeal carcinoma
JP Li, CY Wu, MY Chen, SX Liu, SM Yan… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
… Induction of Th-CXCL13 cells links innate inflammation to immune privilege in tumor-associated …
We added an IL-2-neutralizing antibody into the differentiation mixtures in vitro, which …
We added an IL-2-neutralizing antibody into the differentiation mixtures in vitro, which …
[HTML][HTML] CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer
B Wang, M Wang, D Ao, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
… (CXCL13), originally identified as a B-cell chemokine, plays an important role in the immune
… chemotaxis of nearby responding cells, including the homing and positioning of mature T …
… chemotaxis of nearby responding cells, including the homing and positioning of mature T …
[PDF][PDF] IL-4Rα-expressing B cells are required for CXCL13 production by fibroblastic reticular cells
… fibroblasts in the development of CXCL13+ MRC-like cells and adaptive type 2 immunity in
… the germinal centers and to facilitate antibody production. FDC ablation disrupts proper B …
… the germinal centers and to facilitate antibody production. FDC ablation disrupts proper B …
Immune niche within the peritoneal cavity
Y Okabe - … Niche: Microenvironments Critical for Immune Cell …, 2021 - Springer
… in peritoneal cavity, not only protecting body cavity from infection … in body cavities, whereas
the identification of B-1 cells … in addition to the production of CXCL13 which is essential for B …
the identification of B-1 cells … in addition to the production of CXCL13 which is essential for B …
The potential for CXCL13 in CSF as a differential diagnostic tool in central nervous system infection
… (DCs) and also Th17 cells, it contributes to B cell homing to … and pleural cavity or the
omentum, also in a CXCL13-… of the immune response and thus before intrathecal antibody …
omentum, also in a CXCL13-… of the immune response and thus before intrathecal antibody …