… infected with Plasmodium falciparum malaria were randomly selected. … P: 0.030). Conclusion:
This study reported that the mutant allele CYP2C8*2 influences the emergence of Pfmdr1 …

… malaria recurrences in patients for up to 1 year by passive case detection using the
SIVEP-Malaria platform (the Brazilian official malaria … of Plasmodium falciparum and Plasmodium …

… genetic causality for Plasmodium falciparum resistance against … As frequências dos genótipos
CYP2C8*2 e CYP2C8*3 … interepisode time and pfpm3 and pfmdr1 CNV distribution. .....…

… and CYP2C8 genetic variants influencing AQ metabolism were genotyped. Samples were
additionally genotyped for pfcrt K76T and pfmdr1 … in the Plasmodium falciparum chloroquine …

… been aggravated by the selection of parasites with partial … For example, pfmdr1 N86Y causes
decreased susceptibility … and to a lesser extent by CYP2C8 when compared to CYP3A4 [73]…

… This study aimed to assess the influence of these CYP2C8 … to have had implications on
the choice of first-line treatment in the … CYP2C8*3 status may significantly influence treatment …

… As part of confirmation, genotyping for CYP2C8 SNPs … pfmdr1 in Southeast Asia led to the
substitution of DHA, the active metabolite of artemisinin, and PPQ (38). Plasmodium falciparum …

… treatment for uncomplicated Plasmodium falciparum malaria. … Although the present study
results may have been influenced by … metabolism provides a fertile ground for the selection of P. …

… for uncomplicated Plasmodium falciparum malaria. … the M2 associated with the action of
CYP2C8 on PPQ. (abbreviations: … as pfmdr1 duplications might have a significant influence on …

… patients with severe Plasmodium falciparum malaria in … reduced activity of CYP2B6 and
CYP2C8, with important implications … to influence the selection of parasite antimalarial response …