… Phenytoin is a frequently used drug treatment for epilepsy. Genetic polymorphisms in the
metabolism of phenytoin… These data suggest that CYP2C9*3 has a significant functional impact …

… levels of phenytoin lead to uncontrolled seizures, while high … the effect of CYP2C9 and
CYP2C19 polymorphism on … on prescribing practice and improving treatment decisions, patient …

… following phenytoin administration in epilepsy patients. Based … the duration of treatment of
focal seizures using phenytoin [24]. … CYP2C9 polymorphism has a significant effect on serum …

… for phenytoin treatment, and classified these reasons into seizure (ie, all types of epilepsy
or chronic seizure) or … The effect of genetic polymorphism of cytochrome P450 CYP2C9 on …

… , an impact of the CYP2C9 and CYP2C19 polymorphisms on phenytoin was noticeable. …
The studies, which involved patients, chronically treated with phenytoin, in whom, at least …

… polymorphism affecting CYP2C9 “rs12782374G/A” in the same population to detect the effect
… metabolism, a variation in this gene can reduce phenytoin metabolism, increasing the risk …

… polymorphism in genes coding for CYP2C9 and CYP2C19 in … DPH) form the mainstay of
treating epilepsy, which is a serious … to determine the influence of presence of CYP2C9*3 allele …

… Moreover, our findings open the gate for personalized antiepileptic therapy according to
the pattern of CYP2C9 genotypes/alleles [31]. In contrast to our results, Lakhan et al. studied …

… phenytoin therapy.[ 12 13 ] In the current study, we sought to study the association of CYP2C9*2
and CYP2C9*3 polymorphism … in 4 patients, dermatological side effect in 4 cases, and …

… CYP2C9*3 polymorphism was found to be associated with serious cutaneous ADRs (cADRs)
induced by phenytoin … Plasma PB levels were not influenced by C3435T polymorphism, but …