[HTML][HTML] Insights into the pharmacogenetics of tacrolimus pharmacokinetics and pharmacodynamics
M Brunet, M Pastor-Anglada - Pharmaceutics, 2022 - mdpi.com
… More recently, several genetic polymorphisms in selected SLC and ABC transporter … CYP3A
and ABCB1 genetic variants and the risk of acute rejection [2]. Moreover, although tacrolimus…
and ABCB1 genetic variants and the risk of acute rejection [2]. Moreover, although tacrolimus…
Influence of CYP3A polymorphisms on tacrolimus pharmacokinetics in kidney transplant recipients
I Hannachi, Z Chadli, E Kerkeni, A Kolsi… - The …, 2021 - nature.com
… General, our results propose that the CYP3A polymorphisms have a significant influence
on the Tac bioavaibility in different PT times. That is the reason why we have found interesting …
on the Tac bioavaibility in different PT times. That is the reason why we have found interesting …
Association of genetic variants in CYP3A4, CYP3A5, CYP2C8, and CYP2C19 with tacrolimus pharmacokinetics in renal transplant recipients
Z Wang, M Zheng, H Yang, Z Han, J Tao… - Current Drug …, 2019 - ingentaconnect.com
… of genetic polymorphisms on tacrolimus pharmacokinetics … in CYP3A promoters and
characterization of the genetic basis … /5 genetic score and ABCB1 polymorphisms on tacrolimus …
characterization of the genetic basis … /5 genetic score and ABCB1 polymorphisms on tacrolimus …
[HTML][HTML] The impact of cytochrome P450 3A genetic polymorphisms on tacrolimus pharmacokinetics in ulcerative colitis patients
M Furuse, S Hosomi, Y Nishida, S Itani, Y Nadatani… - PloS one, 2021 - journals.plos.org
… CYP3A4, which encodes CYP3A4, another major enzyme of the CYP3A subfamily involved
in drug pharmacokinetics, has several SNPs related to the metabolic activity of CYP3A4 [15, …
in drug pharmacokinetics, has several SNPs related to the metabolic activity of CYP3A4 [15, …
[HTML][HTML] Beyond Single Nucleotide Polymorphisms: CYP3A5∗3∗6∗7 Composite and ABCB1 Haplotype Associations to Tacrolimus Pharmacokinetics in Black …
DA Brazeau, K Attwood, CJ Meaney, GE Wilding… - … in Genetics, 2020 - frontiersin.org
… of ABCB1 on tacrolimus pharmacokinetics was assessed using haplotype analysis encompassing
the single nucleotide polymorphisms: … both CYP3A5 and ABCB1 polymorphisms was …
the single nucleotide polymorphisms: … both CYP3A5 and ABCB1 polymorphisms was …
Recipient ABCB1, donor and recipient CYP3A5 genotypes influence tacrolimus pharmacokinetics in liver transplant cases
SM Naushad, A Pavani, Y Rupasree, T Hussain… - Pharmacological …, 2019 - Springer
… Effect of the ABCB1 3435C&T polymorphism on tacrolimus concentrations and dosage …
Impact of donor and recipient CYP3A5 and ABCB1 genetic polymorphisms on tacrolimus dosage …
Impact of donor and recipient CYP3A5 and ABCB1 genetic polymorphisms on tacrolimus dosage …
Effect of CYP3A5 and ABCB1 Gene Polymorphisms on Tacrolimus Blood Concentration in Renal Transplant Recipients.
… CYP3A4 and CYP3A5 are the main components of the CYP3A enzymes. The main … to
ABCB1 gene variability [8]. The most common polymorphisms associated with the ABCB1 gene …
ABCB1 gene variability [8]. The most common polymorphisms associated with the ABCB1 gene …
The CYP3A5 and ABCB1 gene polymorphisms in kidney transplant patients and establishment of initial daily tacrolimus dosing formula
Y He, Y Ma, Q Fu, J Liang, X Yu… - Annals of …, 2022 - journals.sagepub.com
… subtype of the CYP3A subfamily and … of tacrolimus are not only weight and CYP3A5 gene
polymorphism. Thus, in this study, we collected the ABCB1 and CYP3A5gene polymorphisms …
polymorphism. Thus, in this study, we collected the ABCB1 and CYP3A5gene polymorphisms …
[HTML][HTML] Association of CYP3A4-392A/G, CYP3A5-6986A/G, and ABCB1-3435C/T Polymorphisms with Tacrolimus Dose, Serum Concentration, and Biochemical …
EV Alatorre-Moreno, AM Saldaña-Cruz… - Genes, 2024 - mdpi.com
… CYP3A4, CYP3A5, and ABCB1 gene polymorphisms were genotyped using qPCR TaqMan…
CYP2C19 and CYP3A enzyme inhibitor that could modify TAC pharmacokinetics: CYP2C19 …
CYP2C19 and CYP3A enzyme inhibitor that could modify TAC pharmacokinetics: CYP2C19 …
Effects of CYP3A5, ABCB1 and POR* 28 polymorphisms on pharmacokinetics of tacrolimus in the early period after renal transplantation
J Ling, LL Dong, XP Yang, Q Qian, Y Jiang, SL Zou… - Xenobiotica, 2020 - Taylor & Francis
… included gene polymorphisms (CYP3A5, ABCB1 3435 C > T, ABCB1 1236 C > T, …
pharmacokinetics parameters of tacrolimus. It is well known that tacrolimus is metabolized by CYP3A …
pharmacokinetics parameters of tacrolimus. It is well known that tacrolimus is metabolized by CYP3A …