… Caenorhabditis elegans as a versatile platform for drug discovery. Its genetic amenability
and ease of transgenesis allows elucidation of MOAs by forward and reverse genetic screens …

… There have been other recent reviews on the use of C. Elegans in drug discovery [14-16], …
models in terms of their toxicity testing and drug discovery. We will consider devices used from …

… exploring nervous system pathologies and as a platform for drug discovery. There is a
particular focus given to describing the existing models of C. elegans for the study of NDevDs and …

… The increasing popularity of C. elegans model in the field of novel drug discovery and
research is attributed to its transparent small size, simple anatomy, short life cycle, and rapid …

… of Target-Based Versus Phenotypic Screening While early drug discovery was mostly a …
healing properties in specific diseases, drug discovery became more scientific at the beginning …

… In the present review, we summarize certain milestones and challenges of the C. elegans
model with focus on drug target identification, anthelmintic drug discovery and identification of …

… novel, early-stage drug discovery approaches to identify drug candidates that can be …
Caenorhabditis elegans is a small roundworm—about 1 mm in length at maturity. The legacy of C…

… system-based drug screening platform is an optimal research platform that can effectively …
on drug screening applications using cell/organ chips and C. elegans-based biochips (C. …

… elegans Snapshot Analysis Platform (CeSnAP), paired with a rapid snapshot acquisition
technique that serves as a simple and versatile workflow to quantify C. elegans behavioral …

… We anticipate the platform described here will further integrate the use of C. elegans … of
mitochondrial function and metabolism of the nematode Caenorhabditis elegans. BMC …