Therapeutic cardiac patches for repairing the myocardium

BW Streeter, ME Davis - … 5: Stem Cells: Translational Science to Therapy, 2019 - Springer
… In the case of CTE, engineered cardiac patches can be generated … recent CTE and cardiac
patch advancements, particularly in … in future research to engineer a successful cardiac patch. …

Chemical engineering of cell therapy for heart diseases

Z Li, S Hu, K Cheng - Accounts of chemical research, 2019 - ACS Publications
… , we will review these three generations of therapeutic strategies (Figure 1). Our most recent
efforts to use chemical engineeringWe have fabricated a vascularized cardiac patch by …

Engineering human cardiac muscle patch constructs for prevention of post-infarction LV remodeling

L Wang, V Serpooshan, J Zhang - Frontiers in cardiovascular …, 2021 - frontiersin.org
… of cardiac patch therapies. Sine large animal models more closely approximate the human
heart's … used to assess arrhythmias in cardiac patch studies (41). Preclinical studies of non-…

Recent development in therapeutic cardiac patches

X Mei, K Cheng - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
we will present the most state-of-the-art cardiac patches and analysis their compositional
details. The therapeutic ingredients will … of ECM for tissue engineering in personalized therapy. …

Recent fabrications and applications of cardiac patch in myocardial infarction treatment

M Li, H Wu, Y Yuan, B Hu, N Gu - View, 2022 - Wiley Online Library
… In this review, we outline the latest advances of the … effects of cardiac patches used in animal
and clinical treatment of … are used as therapeutic cell source for cardiac patch engineering, …

Next generation of heart regenerative therapies: progress and promise of cardiac tissue engineering

MF Tenreiro, AF Louro, PM Alves… - NPJ Regenerative …, 2021 - nature.com
… relevance of 3D maturation-based strategies to the field, we will further detail 3D tissue
fabrication methodologies in this review (see “Fabrication of biomimetic cardiac tissues”). …

A new era of cardiac cell therapy: opportunities and challenges

K Huang, S Hu, K Cheng - Advanced healthcare materials, 2019 - Wiley Online Library
… products, and their role in shaping new clinical approaches for heart tissue engineering, are
… live-cell therapy limitations.133 Thus, we will introduce cardiac patches without live cells (…

Biomaterializing the promise of cardiac tissue engineering

JE Pomeroy, A Helfer, N Bursac - Biotechnology advances, 2020 - Elsevier
… , we discuss various strategies for in vitro fabrication of fECTs and their applications in cardiac
regenerative therapies in … , or patches, has thus been a major research area in therapeutic

4D physiologically adaptable cardiac patch: a 4-month in vivo study for the treatment of myocardial infarction

H Cui, C Liu, T Esworthy, Y Huang, Z Yu, X Zhou… - Science …, 2020 - science.org
… There has been considerable progress in engineering cardiac scaffolds for the treatment of
myocardial infarction (MI). However, it is still challenging to replicate the structural specificity …

Constructing biomimetic cardiac tissues: a review of scaffold materials for engineering cardiac patches

D Sharma, M Ferguson, TJ Kamp, F Zhao - Emergent materials, 2019 - Springer
… patients have shown the potential of ECPs in the treatment of chronic heart failure. However,
several hurdles are still need to be overcome for successful translation of this technology …