[HTML][HTML] A review on machine learning approaches and trends in drug discovery
P Carracedo-Reboredo, J Liñares-Blanco… - Computational and …, 2021 - Elsevier
… Neural Network Model, and from that moment these models … uses a graphical attention
mechanism to learn from relevant drug … It is therefore essential to study toxicological properties as …
mechanism to learn from relevant drug … It is therefore essential to study toxicological properties as …
[图书][B] Biomarkers in toxicology
RC Gupta - 2019 - books.google.com
… systems. This revised and completely updated edition includes both vertebrate and non-vertebrate
species models for toxicological testing … all aspects of toxicology biomarkers Includes …
species models for toxicological testing … all aspects of toxicology biomarkers Includes …
[HTML][HTML] Synthesis and Toxicity of Graphene Oxide Nanoparticles: A Literature Review of In Vitro and In Vivo Studies
A Rhazouani, H Gamrani, M El Achaby… - BioMed Research …, 2021 - hindawi.com
… toxicity of GO in cellular models and biological systems. Moreover, we mention the general
mechanism of its toxicity… Finally, we showed the general mechanism of toxicity, to better …
mechanism of its toxicity… Finally, we showed the general mechanism of toxicity, to better …
[HTML][HTML] Uncovering the complexity mechanism of different formulas treatment for rheumatoid arthritis based on a novel network pharmacology model
K Wang, Y Gao, C Lu, Y Li, B Zhou, X Qin… - Frontiers in …, 2020 - frontiersin.org
… In this study, network pharmacology model was applied to analyze the key gene network …
Moreover, it abstracts the interaction between drugs and target genes into a network model …
Moreover, it abstracts the interaction between drugs and target genes into a network model …
[HTML][HTML] The NCATS BioPlanet–an integrated platform for exploring the universe of cellular signaling pathways for toxicology, systems biology, and chemical genomics
R Huang, I Grishagin, Y Wang, T Zhao… - Frontiers in …, 2019 - frontiersin.org
… Molecular pathways are defined not only by their importance in … toxicological endpoints
may potentially be caused by dysfunction of any pathway operative in human cells, mechanistic …
may potentially be caused by dysfunction of any pathway operative in human cells, mechanistic …
Ethanol and its metabolites: update on toxicity, benefits, and focus on immunomodulatory effects
… This sterile inflammation mechanism may override ethanol’s beneficial effects on the immune
system and accentuate its toxicity. Furthermore, purinergic receptors (which are also able …
system and accentuate its toxicity. Furthermore, purinergic receptors (which are also able …
[图书][B] Nutraceuticals: efficacy, safety and toxicity
RC Gupta, R Lall, A Srivastava - 2021 - books.google.com
… role of hormesis in neuroprotection 5 Modulation of the Nrf2-ARE pathway as a mechanism
of … 2 as a potential novel mechanism of quercetin neuroprotection 6 The issue of metabolites …
of … 2 as a potential novel mechanism of quercetin neuroprotection 6 The issue of metabolites …
In-silico modeling in drug metabolism and interaction: Current strategies of lead discovery
H Roy, S Nandi - Current Pharmaceutical Design, 2019 - ingentaconnect.com
… (ADME) as well as toxicity studies which take 5-15 years with the … PBPK modeling is a
mechanistic approach that has been … Dmitry et al. developed a neural network model for an early …
mechanistic approach that has been … Dmitry et al. developed a neural network model for an early …
Computational network biology: data, models, and applications
… studying the biological systems from network biology has attracted much attention in recent
years, and networks have long been central to our understanding of biological systems, in …
years, and networks have long been central to our understanding of biological systems, in …
[HTML][HTML] Pesticides and pollinators: A socioecological synthesis
… literature and providing empirical case studies. We then propose … engagement, (2) mechanistic
study of pesticide exposure, (3) … , toxicological, and ecological dimensions of the system. …
study of pesticide exposure, (3) … , toxicological, and ecological dimensions of the system. …