… has a low risk of muscle problems when used without statins. … Target LDL-C is still 1.8 mmol/L,
but more aggressive therapy with … Lipid interventions with statins lower cardiovascular risk. …

… statin therapy currently forms the mainstay of lipid-lowering … Ischemia Reduction With
Aggressive Cholesterol Lowering) … Although our risk prediction abilities have improved, problems …

… Patients typically require a more aggressive lipid suppression medication … statin therapy,
certain patients may not achieve adequate reduction or may develop adverse effects to statins…

… myopathy with other lipid-lowering therapy, high-dose statin therapy, … problems or report the
effect of statin therapy on CK levels. … aggression, agitation, irritability, mood changes, violent …

… Comparisons with other statin guidelines revealed that statin … Unfortunately, there are a
number of problems with the nonselective … In the Cholesterol Treatment Trialists individual meta-…

… implications that come with the aggressive reduction of its level in … to issue black-box warnings
on statins regarding the risk of … largest statin survey ever conducted by the National Lipid …

… individual is based on the results of the analysis of … Regarding the adverse effects, the
musculoskeletal problems … who are intolerant with statins, further lipid-lowering therapies still need …

… If more aggressive reductions are necessary, high-… statin use with various health-related
problems including cognitive impairment, participants were also on non-statin lipid-lowering …

… updated to recommend more aggressive reduction of LDL-C … specific recommendations
(such as the exact lipid lowering … practice regarding setting specific lipid lowering goals, which …

… strategies of lipids modifying drugs (statins, proprotein … the problems are usually reversible
when the dose of statin is … PPARδ-specific agonists have revealed an important role for …