An insight into the role of apoptosis and autophagy in nitric oxide–induced articular chondrocyte cell death

E Akaraphutiporn, T Sunaga, EC Bwalya… - Cartilage, 2021 - journals.sagepub.com
through the caspase-independent pathway. Our data suggest that autophagy is a protective
mechanism in the pathogenesis … in chondrocytes treated with SNP alone or a combination of …

MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint

H Yang, YI Wen, M Zhang, Q Liu, H Zhang, J Zhang… - Autophagy, 2020 - Taylor & Francis
autophagy program leading to cell death [Citation35,Citation36]. Suppression of autophagy
genes leads to cell death in … Our combined molecular and biochemical in vitro and in vivo …

Autophagy is involved in mesenchymal stem cell death in coculture with chondrocytes

CA Paggi, A Dudakovic, Y Fu, CG Garces… - Cartilage, 2021 - journals.sagepub.com
cell death of MSCs in cocultures. Pellets containing the combination of human chondrocytes
… the apoptotic or autophagy pathways. Our data show a clear prevalence in activation of the …

Apoptosis, autophagy, NETosis, necroptosis, and pyroptosis mediated programmed cell death as targets for innovative therapy in rheumatoid arthritis

J Zhao, P Jiang, S Guo, SJ Schrodi, D He - Frontiers in immunology, 2021 - frontiersin.org
… hand, enhanced cell death of osteoblasts/chondrocytes and … cells combined with Fas
expressed on the human osteoblast … relationship between a variety of PCD and RA pathogenesis. …

Caspase inhibition affects the expression of autophagy-related molecules in chondrocytes

B Vesela, E Svandova, A Ramesova… - Cartilage, 2021 - journals.sagepub.com
… the programmed cell death of chondrocytes. Beclin-1, one of the main … Reaction mixture
contained the one-step master mix gb Ideal … Additionally, B2m may contribute to pathogenesis of …

Noncoding RNAs: new regulatory code in chondrocyte apoptosis and autophagy

S Jiang, Y Liu, B Xu, Y Zhang… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
… of OA, but a combination of cellular changes and biomechanical … differences between
apoptotic and autophagic cell death … for investigating the pathogenesis and identifying potential …

BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy

Z Ma, D Wang, J Weng, S Zhang, Y Zhang - Journal of Orthopaedic …, 2020 - Springer
… and lead to cell death through apoptosis and autophagy [14,15… BNIP3 combined with ceramide
could induce the autophagy … , the apoptosis of chondrocytes is also one of the pathogenic

Chondrocyte death involvement in osteoarthritis

S Salucci, E Falcieri, M Battistelli - Cell and tissue research, 2022 - Springer
… this type of death is a combination between the classical apoptosis and autophagy (Almonte-…
morphological features of cell death when chondrocytes differentiate in a micromass model. …

Effects of autophagy on apoptosis of articular chondrocytes in adjuvant arthritis rats

R Zhou, F Zhu, X Wu, S Song, Y Chen… - Journal of cellular …, 2019 - Wiley Online Library
… articular chondrocytes undergo cell death during the progression of arthritis via a combination
of autophagy and apoptosis. … during the pathogenesis of RA via suppressing chondrocyte

[HTML][HTML] Autophagy attenuates osteoarthritis in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling

J Yan, G Feng, Y Yang, D Ding, L Ma… - Biomolecules and …, 2023 - ncbi.nlm.nih.gov
At present, the etiology and pathogenesis of OA have not … combination of biological and
mechanical factors [3]. Pathological … autophagy can lead to abnormal cell function and cell death […