[HTML][HTML] HTLV-1 infection: An emerging risk. Pathogenesis, epidemiology, diagnosis and associated diseases

E Eusebio-Ponce, E Anguita… - Revista Española de …, 2019 - ncbi.nlm.nih.gov
HTLV-1 life cycle: HTLV-1 virion interacts with the target cell surface receptors GLUT1/
HSPG/NRP-1 via the HTLV-1 … viruses enter the synaptic cleft and interact with cellular receptors. …

HTLV-1 infection and pathogenesis: new insights from cellular and animal models

G Forlani, M Shallak, RS Accolla… - International Journal of …, 2021 - mdpi.com
… , which is typically associated only with HTLV-1 infection, … proteins in HTLV-1 infectivity
and pathogenicity. p8 and p12, … early steps of infection, at the entry step, the tropism is almost …

HIV-1 and HTLV-1 transmission modes: Mechanisms and importance for virus spread

S Kalinichenko, D Komkov, D Mazurov - Viruses, 2022 - mdpi.com
associated HTLV-1 viral particles fuse with the plasma membrane of target cells, or are
internalized and enter … whether this cellular model reflects the cell-to-cell transmission of HTLV-1, …

HTLV1 oncovirus‐host interactions: From entry to the manifestation of associated diseases

S Ahmadi Ghezeldasht, SAA Shamsian… - Reviews in medical …, 2021 - Wiley Online Library
HTLV-1 recruits many cellular and viral genes and form a protein ring in the … entry and
effective virus dissemination, and promote tissue damages involved in the HAM/TSP pathogenicity

Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)

S Ahmadi Ghezeldasht, DJ Blackbourn… - Critical Reviews in …, 2023 - Taylor & Francis
… cell entry to integrate into the host genome as the HTLV-1cellular factors involved in cell
survival and proliferation and malignancy. The HTLV-1-HBZ is a complicated regulatory factor

Identification of joint gene players implicated in the pathogenesis of HTLV-1 and BLV through a comprehensive system biology analysis

F Ashrafi, SA Ghezeldasht, MZ Ghobadi - Microbial pathogenesis, 2021 - Elsevier
… sets, hub genes, and modules in pathogenicity were screened. … Upon virus entry and
localization in host cells, subclinical … protein to mediate cellular transformation and metastasis in …

Extracellular vesicles from HTLV-1 infected cells modulate target cells and viral spread

DO Pinto, S Al Sharif, G Mensah, M Cowen, P Khatkar… - Retrovirology, 2021 - Springer
… efforts to understand HTLV-1 pathogenicity, more research is … examined whether HTLV-1
EVs alone are sufficient to enter (… the potential mechanisms of cellular damage, we sought to …

… insights into human T‐lymphotropic virus type‐1 (HTLV1) pathogenesis‐host interactions in the manifestation of HTLV1associated myelopathy/tropical spastic …

S Ahmadi Ghezeldasht, A Mosavat… - Reviews in Medical …, 2024 - Wiley Online Library
… diseases, the virulence and pathogenicity of this virus are yet … The HTLV-1 envelope is
crucial for entering target cells and initiating … The cellular targets of HTLV-1 infections in vivo are …

Extracellular vesicles in HTLV-1 communication: the story of an invisible messenger

S Al Sharif, DO Pinto, GA Mensah, F Dehbandi… - Viruses, 2020 - mdpi.com
… players involved are cell surface receptors and other cellular … The pathogenicity of HU is
characterized by a significant … -mediated endocytosis regulates HTLV-1 entry in immature DCs…

Co-Infection and Cancer: Host–Pathogen Interaction between Dendritic Cells and HIV-1, HTLV-1, and Other Oncogenic Viruses

TH Mulherkar, DJ Gómez, G Sandel, P Jain - Viruses, 2022 - mdpi.com
… by affecting cellular gag expression. Antiretroviral therapy (ART) is successful in controlling
HIV disease but has little effect on HTLV-1… of HTLV-1 immunopathogenesis through entry and …