The evidence for and consequences of metabotropic glutamate receptor heterodimerization

TW McCullock, PJ Kammermeier - Neuropharmacology, 2021 - Elsevier
… the donor and acceptor molecules can be detected indicating the receptors may form a …
within the same cell, and in some cases, localized to the same cellular compartments as a …

Recent Advances in the Clinical Translation of Silicon Fluoride Acceptor (SiFA) 18F-Radiopharmaceuticals

L Gower-Fry, T Kronemann, A Dorian, Y Pu… - Pharmaceuticals, 2021 - mdpi.com
consequences in vivo [47]. Further, it is a general rule of thumb that only 1% of receptors
should … (SSTRs), which are characteristically over-expressed on the cell surfaces of these tumor …

Molecular diagnostic assays and clinicopathologic implications of MET exon 14 skipping mutation in non–small-cell lung cancer

EK Kim, KA Kim, CY Lee, S Kim, S Chang, BC Cho… - Clinical lung cancer, 2019 - Elsevier
… , is a receptor tyrosine kinase that plays a fundamental role in regulating development and
cell … Most mutations were deletions, which occurred at a splice donor or acceptor, and 2 cases …

Light-activated chimeric GPCRs: limitations and opportunities

AM Tichy, EJ Gerrard, PM Sexton, H Janovjak - Current opinion in …, 2019 - Elsevier
… may have profound consequences on how cell behavior is … In summary, acceptors other than
rho may permit new types … inter-class chimeras as acceptor and donor receptors have lower …

Characterization of splice-altering mutations in inherited predisposition to cancer

S Casadei, S Gulsuner, BH Shirts… - Proceedings of the …, 2019 - National Acad Sciences
… or silencers or introduce new splice acceptors or donors. Multiple … , with biological and clinical
consequences that can range … , it could be necessary to grow cell lines from other tissues. …

Protective effect of CXCR4 antagonist CX807 in a rat model of hemorrhagic stroke

SJ Yu, KJ Wu, YS Wang, JS Song, CH Wu… - International Journal of …, 2020 - mdpi.com
… CX807 may have clinical implications for the treatment of hemorrhagic stroke. … The PathHunter
® β-Arrestin cell lines expressing chemokine receptors were used. The functional reporter …

Structural, molecular, and functional alterations of the blood-brain barrier during epileptogenesis and epilepsy: a cause, consequence, or both?

W Löscher, A Friedman - International journal of molecular sciences, 2020 - mdpi.com
… the inductive influence of neighboring cell types, including … , enzymes and receptors regulate
molecular and cellular traffic … hydrogen bond donors and acceptors and the polar surface …

Considerations about hypoxic changes in neuraxis tissue injuries and recovery

SI Stoica, C Bleotu, V Ciobanu, AM Ionescu, I Albadi… - Biomedicines, 2022 - mdpi.com
receptors as toll-like receptors (TLR-2, TRL-4). HMGB1 can be altered by redox reactions
with implications for acute and chronic cellular … acids can be proton acceptors from anaerobic …

[HTML][HTML] Metabolic implications of oxidative stress and inflammatory process in SARS-CoV-2 pathogenesis: therapeutic potential of natural antioxidants

GE Forcados, A Muhammad, OO Oladipo… - Frontiers in Cellular …, 2021 - frontiersin.org
… SARS-CoV-2 entry into a host cell involves a number of conformational changes requiring
binding of a virus particle to angiotensin-converting enzyme (ACE-2) receptor on the cell

SUMO3 modification by PIAS1 modulates androgen receptor cellular distribution and stability

N Yang, S Liu, T Qin, X Liu, N Watanabe… - Cell Communication and …, 2019 - Springer
… , the SUMO-acceptor lysine 386 on AR, together with ubiquitin-acceptor lysine 845, … Moreover,
PIAS1 itself is modified by SUMO3 overexpression, and mutation of SUMO-acceptor lysine …