… versus platinum, fluorouracil, and cetuximab as first-line treatment in patients with recurrent or metastatic head and neck squamous-cell carcinoma (GORTEC 2014-01 …

J Guigay, A Aupérin, J Fayette, E Saada-Bouzid… - The Lancet …, 2021 - thelancet.com
… Platinum-based chemotherapy plus cetuximab in head and neck cancer. … versus cetuximab
with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck

[HTML][HTML] Cetuximab-containing combinations in locally advanced and recurrent or metastatic head and neck squamous cell carcinoma

M Taberna, M Oliva, R Mesía - Frontiers in oncology, 2019 - frontiersin.org
Cetuximab remains to date the only targeted therapy approved for the treatment of head and
neck squamous cell carcinoma (… have been tested in HNSCC, cetuximab, an IgG1 subclass …

… alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a …

B Burtness, KJ Harrington, R Greil, D Soulières… - The Lancet, 2019 - thelancet.com
Head and neck squamous cell carcinoma (HNSCC) includes cancers of the oral cavity,
oropharynx, hypopharynx, and larynx. Locoregional HNSCC is treated with curative intent, …

Nivolumab in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: efficacy and safety in CheckMate 141 by prior cetuximab use

RL Ferris, L Licitra, J Fayette, C Even… - Clinical Cancer …, 2019 - AACR
… Here, we assessed outcomes with nivolumab, by prior cetuximab exposure, in patients with
recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) who …

[HTML][HTML] … with chemotherapy plus cetuximab in Chinese patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck: Efficacy and safety …

Y Guo, Y Luo, Q Zhang, X Huang, Z Li, L Shen… - … Journal of Cancer, 2021 - Elsevier
… new cases of head and neck cancers worldwide, with … percent of head and neck cancers are
squamous cell carcinoma (… {5-FU}] plus cetuximab followed by cetuximab maintenance until …

Cetuximab in locally advanced head and neck squamous cell carcinoma: Biological mechanisms involved in efficacy, toxicity and resistance

E Muraro, G Fanetti, V Lupato, V Giacomarra… - Critical Reviews in …, 2021 - Elsevier
… Currently, cetuximab associated with radiotherapy is limited to the … cetuximab efficacy in
this cancer setting are still lacking. This review focuses on the mechanisms of action of cetuximab

Pembrolizumab plus cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma: an open-label, multi-arm, non-randomised …

AG Sacco, R Chen, FP Worden, DJL Wong… - The Lancet …, 2021 - thelancet.com
… Pembrolizumab (PD-1 inhibitor) and cetuximab (EGFR … or metastatic head and neck squamous
cell carcinoma (HNSCC). … or metastatic squamous cell carcinoma of the head and neck

[HTML][HTML] … in combination with cetuximab for the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: evidence, advantages, and …

J Guigay, M Tahara, L Licitra, U Keilholz… - Frontiers in …, 2019 - frontiersin.org
Cancer of the head and neck accounts for >550,000 new cases annually worldwide (1, 2).
About 90% of all head and neck cancers are squamous cell carcinomas … of the head and neck (…

Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised …

EEW Cohen, D Soulières, C Le Tourneau, J Dinis… - The Lancet, 2019 - thelancet.com
… -L1) monotherapy for squamous cell carcinoma of the head and neck—the CheckMate 141
study of nivolumab versus investigator's choice of docetaxel, methotrexate, or cetuximab for …

[HTML][HTML] Biomarkers of cetuximab resistance in patients with head and neck squamous cell carcinoma

O Leblanc, S Vacher, C Lecerf, E Jeannot… - Cancer Biology & …, 2020 - ncbi.nlm.nih.gov
… Objective: In patients with head and neck squamous cell carcinoma (HNSCC), cetuximab
[a … While biomarkers of resistance to cetuximab have been identified in metastatic colorectal …