… in utilizing nucleic acids, including DNA and RNA molecules, … that could avoid cleavage
by nucleic acid exonucleases. In the … -transfected cells, suggesting a robust gene transfection …

… Finally, preliminary transfection efficiency studies with cell … the film hydration method by
producing a thin lipid film with … However, concerning the stability issues of lipoplexes containing …

… The main challenge limiting the widespread use of … Organic solvents were then removed in
vacuo, the lipid film obtained was … Thus, we compared the transfection efficiency of lipoplexes …

… a great challenge to explore new cationic lipid-independent … was added to the dried lipid
film to reach a final concentration … (ELISA), indicating the transfection capacity of our mRNA-…

… challenges of using nucleic acids as vaccines relate to their structure and function. Unlike
protein antigens, long protein-encoding nucleic acids … greater transfection efficiency than the …

… One challenge in evaluating skin penetration of wide variety of nanostructures is the
choice … Thin lipid film for liposomes was formed by dissolving 1,2-dipalmitoyl-sn-glycero-3-…

… One major challenge relies on nucleic acids’ safe and … There are many types of polymeric
and lipid-based nonviral … have shown promising results with high transfection rates due to their …

… It has also been reported that an increase in transfection … some lipid-based siRNA delivery
techniques, challenges faced … and lipids has been demonstrated to bind nucleic acid and …

… indicate difficulties of their cellular uptake. … transfection efficiency on HeLa cell line, we
observed that by increasing the ratio of H 2 N-PEG-NH 2 from 0.1 to 1 equivalent the transfection …

… drugs is associated with substantial issues such as poor absorption… In the system, liposome
was synthesized using the thin-film … with nucleic acid was examined to check the transfection …