Development of New Separation Methods for Personalized Medicine

C Zhang - 2019 - search.proquest.com
… for the analysis of imazethapyr, IgG, digoxin… LC-MS/MS to identify biomarkers for diabetic
nephropathy in human plasma[141], and multi-lectin columns have been utilized in the analysis

Clinical Applications

C Fang, H Lu - … –Based Glycoproteomics and Its Clinic Application, 2021 - taylorfrancis.com
LC-MS/MSbiosimilar mAbs are becoming available for a single originator drug, so it is
critical to demonstrate their similarity with the reference product to ensure its quality characteristics

[图书][B] Targeted detection of secretion pathway protein interactions for therapeutic production and cellular engineering

CM Robinson - 2020 - search.proquest.com
Using proximity dependent labeling coupled to LC-MS/MS, … concentrator prior to LC-MS/MS
analysis. Dried peptides were … Biosimilars will maintain momentum in a highly competitive …

Recent advances of functional proteomics in gastrointestinal cancers-a path towards the identification of candidate diagnostic, prognostic, and therapeutic molecular …

M Abyadeh, A Meyfour, V Gupta… - International journal of …, 2020 - mdpi.com
… mass tag (TMT) reagents followed by LC-MS/MS analysis. Their strategy was able to identify
… Stewart and colleagues in 2019 used an antibody-based phosphoproteomic platform to …

Recovery of rare cells and single cells analysis: different opportunities and challenging applications

R Maiocchi - 2021 - usiena-air.unisi.it
… To counteract the ‘biosimilars effect’, pharmaceutical … To assess the efficacy of the supernatants
of the miniaturized and … all the peptides detected in the LC-MS/MS analysis. The results …

Protein and polypeptide mediated delivery to the eye

SA Attia, JA MacKay - Advanced drug delivery reviews, 2022 - Elsevier
… (SDS-PAGE) and nano-LC/MS/MS. In a subsequent study, … Using proteomics analysis to
study the effect of ranibizumab … Generic biosimilars of ranibizumab have faced complications, …

[引用][C] From Bench to Bedside: Development of a MAPPs assay-based personalized healthcare tool to evaluate the clinical immunogenicity of therapeutic antibodies

K Hartman - 2023 - IRC-Library, Information Resource …

“Small is beautiful”–the significance of reliable determination of low-abundant therapeutic antibody glycovariants

K Böttinger, C Regl, V Schäpertöns, E Rapp… - 2024 - chemrxiv.org
… and accessibility in glycosylation analysis, emphasizing the … the S-trap protocol (mini) according
to manufacturer’s … demonstrated through its application to two additional therapeutic IgG

[HTML][HTML] From synthesis to characterization of site-selective PEGylated proteins

LH Belén, CO Rangel-Yagui… - Frontiers in …, 2019 - frontiersin.org
… In addition, the main assay methods that can be applied for the characterization of
PEGylated molecules in complex biological samples are also summarized in this paper. …

[PDF][PDF] New studies on protein loaded VPG as controlled release systems

W Liu - 2020 - edoc.ub.uni-muenchen.de
… In biomolecules analysis, the bioactivity and bio-affinity analysis is a very important part
during the formulation efficacy and stability study, and the organic solvents are not compatible …