… knee and hip osteoarthritis, we analyzed the methylation profiles in cartilage of 16 OA hip
samples, 19 control hip … With the mRMR analysis, we identified the top 300 most representative …

… those in HumanMethylation27; however, the sample size was relatively small (5 patients
with hip OA, 6 patients with knee OA and 7 hip cartilage samples) [15]. Rushton et al. profiled …

… For osteoporosis, this would be bone, but for osteoarthritis, the tissue of interest is less … the
possibility of clustering a subset of patients characterized by methylation differences in (or near…

… The aim of this study was to characterize the genome-wide DNA methylation profile of hip
cartilage obtained from … Primary osteoarthritis (OA) is a chronic degenerative joint disease …

… enrichment analysis using Ingenuity Pathway Analysis (IPA) to … Second, our analysis was
based on whole blood samples … ) or to cartilaginous and bone tissue related to OA disease (eg …

… When we previously used microarray analysis to explore gene expression changes in normal
and OA cartilage of hip and knee, we similarly found a limited overlap (approximately 10%…

… osteoarthritis-affected individuals undergoing knee replacement surgery. We perform an
epigenome-wide association study of knee cartilage … ID to ensure paired analysis design and 18 …

… commonly by treating the DNA with bisulfite followed by analysis via Illumina 450K microarray
(… Volcano plots for DEGs between osteoarthritis and normal cartilage from the datasets (A) …

… We used ChAMP methylation analysis and the Limma … and human knee cartilage samples
in OA. Function enrichment … reporting the DNA methylome in OA of the knee and hip revealed …

… DNA methylation patterns in femur bone and cartilage of age-matched female baboons, 5
with and 5 without knee … array in identifying DNA methylation patterns in baboon DNA and of …