Chemerin regulates normal angiogenesis and hypoxia-driven neovascularization

C Ben Dhaou, K Mandi, M Frye, A Acheampong… - Angiogenesis, 2022 - Springer
… of chemerin on physiological angiogenesis in vivo, we used a transgenic mouse model
described earlier, in which a bioactive form of chemerin is … Overexpression of chemerin promotes

Chemerin and cancer

O Treeck, C Buechler, O Ortmann - International journal of molecular …, 2019 - mdpi.com
… in vitro experiments confirmed the apoptotic effect of chemerin … the reported tumor-promoting
angiogenic effects of this … -promoting effect of chemerin in gastric cancer. Both high …

Neutrophils regulate tumor angiogenesis in oral squamous cell carcinoma and the role of Chemerin

F Gao, Y Feng, X Hu, X Zhang, T Li, Y Wang… - International …, 2023 - Elsevier
… In vivo experiments demonstrated that Chemerin may promote tumor growth by regulating
tumor angiogenesis. In … Neutrophils potentially contribute to angiogenesis through MEK/ERK …

[HTML][HTML] The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis

I Dubois-Vedrenne, D Al Delbany, O De Henau… - Oncotarget, 2021 - ncbi.nlm.nih.gov
Chemerin was reported to promote the formation of capillary-… of chemerin on angiogenesis
was also reported in vivo in a … Chemerin was previously reported to promote angiogenesis

Chemerin as a modulator of angiogenesis and apoptosis processes in the corpus luteum of pigs: an in vitro study

E Rytelewska, M Kiezun, E Zaobidna… - Biology of …, 2021 - academic.oup.com
chemerin may also affect angiogenesis and apoptosis processes. Chemerin may promote
angiogenesisChemerin may promote apoptosis by activating nuclear factor kappa B (NF-κB), …

Chemerin promotes the pathogenesis of preeclampsia by activating CMKLR1/p-Akt/CEBPɑ axis and inducing M1 macrophage polarization

ZS Ji, H Jiang, Y Xie, QP Wei, XF Yin, JH Ye… - Cell biology and …, 2022 - Springer
… to examine whether chemerin, by promoting M1 macrophage … and migration and angiogenesis
of vascular endothelial cells, … the in vivo effect of CMKLR1 inhibitor on chemerin-induced …

[HTML][HTML] Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells

L Jun, S Lin-Lin, S Hui - Molecular Vision, 2021 - ncbi.nlm.nih.gov
… in vitro cell experiments cannot perfectly simulate the complicated in vivo microenvironment
… Therefore, we think that chemerin may promote the angiogenic process in DR by regulating …

More than an adipokine: the complex roles of chemerin signaling in cancer

KB Goralski, AE Jackson, BT McKeown… - International journal of …, 2019 - mdpi.com
Chemerin can also promote tumor growth via the recruitment … and stimulation of angiogenesis
pathways in endothelial cells… in vitro studies support a tumor-promoting role of chemerin

Role of chemerin in cardiovascular diseases

MT Macvanin, M Rizzo, J Radovanovic, A Sonmez… - Biomedicines, 2022 - mdpi.com
Chemerin promotes angiogenesis by stimulating the endothelial cells’ proliferation while …
processes is illustrated by in vitro findings that chemerin stimulation increases reactive oxygen …

Chemerin-induced angiogenesis and adipogenesis in 3 T3-L1 preadipocytes is mediated by lncRNA Meg3 through regulating Dickkopf-3 by sponging miR-217

X Huang, C Fu, W Liu, Y Liang, P Li, Z Liu… - Toxicology and Applied …, 2019 - Elsevier
… adipogenesis and angiogenesis was explored via the in vitro cellular transfections. … chemerin
and Meg3 expression exerts the synergistic effect on promoting proliferation, angiogenesis