The clinicopathological and prognostic value of CXCR4 expression in patients with lung cancer: a meta-analysis

L Qiu, Y Xu, H Xu, B Yu - BMC cancer, 2022 - Springer
… poor OS was obvious in non-small cell lung cancer patients (HR 1.59, … In the staining pattern
subgroup analysis, CXCR4CXCR4, a type of chemokine receptors, is widely expressed in …

… expression in lung carcinogenesis: Evaluating gender-specific differences in survival outcomes based on CXCR4 expression in early stage non-small cell lung cancer …

AS Fung, K Kopciuk, ML Dean, A D'Silva, S Otsuka… - Plos one, 2021 - journals.plos.org
… with high CXCR4 expression. This study quantifies CXCR4 expression in early stage disease
Chemokine receptor CXCR4 expression and lung cancer prognosis: a meta-analysis. Int J …

[HTML][HTML] High CXCR4 expression predicts a poor prognosis in resected lung adenosquamous carcinoma

Q Zhu, R Luo, J Gu, Y Hou, Z Chen, F Xu… - … of Cancer, 2020 - ncbi.nlm.nih.gov
… CXC chemokine receptor 4 (CXCR4) is a 352 amino acid rhodopsin-like G … expression of
CXCR4 is associated with the metastatic potential of human non-small cell lung cancer cells. …

Clinical significance of chemokine receptor CXCR4 and CCR7 mRNA expression in patients with colorectal cancer

S Nagasawa, K Tsuchida, M Shiozawa… - Anticancer …, 2021 - ar.iiarjournals.org
… about 80% of CRC cases are diagnosed at an early stage and are curable. Surgery is the first
… -CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases. Am J …

Pentixafor PET/CT for imaging of chemokine receptor 4 expression in esophageal cancer–a first clinical approach

P Linde, C Baues, S Wegen, M Trommer, A Quaas… - Cancer Imaging, 2021 - Springer
… to predict response to chemotherapy at an early stage of treatment… to visualize the chemokine
receptor CXCR4 is feasible in both … cancer, non-small cell lung cancer, prostate cancer, …

Correlation between Chemokine CXCL-12 and its Receptor CXCR4 Expression is Associated with Clinical Prognosis of Gastric Cancer.

G Xu, K Lu, M Shen, Q Zhang, W Pan… - Clinical …, 2020 - search.ebscohost.com
… Among these, CXC chemokine receptor 4 (CXCR4) and … for patients with gastric cancer,
especially for early stage. Recent … tumors (eg, breast cancer, non-small cell lung cancer) [18,19]…

CXCR4/MIF axis amplifies tumor growth and epithelial-mesenchymal interaction in non-small cell lung cancer

B Jäger, D Klatt, L Plappert, H Golpon, S Lienenklaus… - Cellular …, 2020 - Elsevier
chemokine receptor type 4 (CXCR4) has been shown in several cancers, including non-small
cell lung cancer … Multiple studies indicate that high expression of CXCR4 of various cancer

Cytokines, chemokines and their receptors in regulation of responses to anticancer therapies in Non-Small Cell Lung Cancer

A Vaughan - 2023 - figshare.le.ac.uk
… The Cancer Genome Atlas database analysis combined with the Meso Scale Discovery …
and the chemokine CXCL1 were highly expressed in LUAD and LUSC. Their cognate receptors

… PET/CT imaging for in vivo CXCR4 receptor mapping in different lung cancer histologic sub-types: correlation with quantitative receptors' density by immunochemistry …

A Watts, B Singh, H Singh, A Bal, H Kaur… - European Journal of …, 2023 - Springer
… small cell lung cancer (SCLC) from non-small cell lung cancer (… is CXCR4—a chemokine
receptor that is widely expressed in … supported by the matching pattern of [ 68 Ga]Ga-Pentixafor …

[HTML][HTML] Exploring the evolution of T cell function and diversity across different stages of non-small cell lung cancer

CY Chang, SC Chang, YF Wei, YT Tseng… - … Journal of Cancer …, 2024 - ncbi.nlm.nih.gov
Early-stage lung cancer was defined as carcinoma in situ (Tis), … Targeting specific chemokine
receptors has shown … These findings suggest that the CXCL12-CXCR4 biological axis …