Individualising the use of radiotherapy for the treatment of people with Hodgkin lymphoma

R Shakir - 2022 - ora.ox.ac.uk
Hodgkin lymphoma is a cancer of the lymphatic system that typically affects young adults.
Chemotherapy and radiotherapy are both highly effective treatments, and 80-90% of patients …

Nivolumab and AVD in Early-Stage Unfavorable Hodgkin Lymphoma: Follow-up Analysis of the Randomized GHSG Phase II Nivahl Trial

PJ Bröckelmann, I Bühnen, J Meissner… - Blood, 2022 - ashpublications.org
… , INDIE will be the first trial investigating a chemo- and radiotherapy-free 1 st -line HL …
Membership on an entity's Board of Directors or advisory committees; BMS: Honoraria, Membership

Pembrolizumab and chemotherapy in newly-diagnosed, early unfavorable or advanced stage classic Hodgkin lymphoma: the phase 2 Keynote-C11 study

RH Advani, A Avigdor, A Sureda, D Lavie, S Hohaus… - Blood, 2022 - ashpublications.org
… AVD chemotherapy and pembrolizumab consolidation in pts with untreated, early unfavorable
or advanced-stage cHL without radiotherapy… committees; MSD: Membership on an entity's …

Frontline PET-directed therapy with Brentuximab Vedotin plus AVD Followed By Nivolumab consolidation in patients with limited stage Hodgkin lymphoma

SI Park, SM Ansell, S Giri, J Svoboda, SD Smith… - Blood, 2022 - ashpublications.org
… cytotoxic chemotherapy and radiation therapy while retaining … strategies may involve radiation
or chemotherapy escalation. … committees; Epizyme: Membership on an entity's Board of …

Nonclonal chromosome aberrations and genome chaos in somatic and germ cells from patients and survivors of hodgkin lymphoma

S Frias, S Ramos, C Salas, B Molina, S Sánchez… - Genes, 2019 - mdpi.com
… At the cellular level, ionizing radiation acts directly breaking … the error-prone nonhomologous
end joining (NHEJ) and may … including aging, chemotherapy, and radiation can cause an …

Involvement of classic and alternative non-homologous end joining pathways in hematologic malignancies: targeting strategies for treatment

M Valikhani, E Rahimian, SE Ahmadi… - … Hematology & Oncology, 2021 - Springer
… -joining (NHEJ), homologous recombination (HR), and other minor pathways such as alternative
end-joining … , especially resistant clones, to radiation or chemotherapy agents. However, …

Brentuximab vedotin combined with chemotherapy in newly diagnosed, early-stage, unfavorable-risk Hodgkin lymphoma: extended follow-up with evaluation of …

R Stuver, L Michaud, C Casulo, RH Advani, EL Budde… - Blood, 2022 - ashpublications.org
… by radiation and autoSCT. The other patient had a negative biopsy of PET4 disease and …
Membership on an entity's Board of Directors or advisory committees; SecuraBio: Honoraria…

SCR7, an inhibitor of NHEJ can sensitize tumor cells to ionization radiation

V Gopalakrishnan, S Sharma, U Ray… - Molecular …, 2021 - Wiley Online Library
… end joining (NHEJ), one of the major DNA double-strand break repair … Hodgkin's
lymphoma and non-Hodgkin's lymphoma (NHL), radiotherapy is often followed by chemotherapy

Multicenter analysis of geriatric fitness and real-world outcomes in older patients with classical Hodgkin lymphoma

VM Orellana-Noia, K Isaac, MK Malecek… - Blood …, 2021 - ashpublications.org
… This study suggests conventional chemotherapy regimens … with radiotherapy and those who
received radiotherapy alone. … of directors or advisory committee membership for Bayer. JBC …

[HTML][HTML] Management of Hodgkin lymphoma in a sickle cell patient: a case report

F Ashraf, P Kancharla, M Goldfinger - Case Reports in Oncology, 2019 - karger.com
… cell disease. We present our choice of chemotherapy as an effective treatment for Hodgkin’s
… severity and involves combination chemotherapy and radiation. For favorable early-stage …