… Engineering immune cells to target cancer is a rapidly advancing technology. The first
commercial products, chimeric-antigen receptor (CAR) T cells, are now approved for hematologic …

… a potential therapeutic target for gastric cancer and other cancer types. The aim of our study
was to elucidate whether chimeric antigen receptor T (CAR T) cells redirected to CLDN18.2 …

… to inactivate NK cells [23]. Engineering NK cells to express a chimeric antigen receptor (CAR)
may … Although several approaches including CAR T cells, checkpoint inhibitors, antibodies, …

… Cellular immunotherapy plays an indispensable role in cancer treatment. Chimeric antigen
receptor (CAR)–engineered T cells therapy, especially for the treatment of hematological …

… growth factor receptor 2 chimeric antigen receptor T cells (HER2.CAR-T) and CD19.CAR-…
Human epidermal growth factor receptor 2 chimeric antigen receptor T cells (HER2.CAR-…

… T-cell escape of tumor cells lacking T-cell antigen or APPM expression, we generated tumor
cells susceptible to killing by TCR-engineered T cells. … encoding HLA or antigen required for …

… immunoreceptor with Ig and ITIM domains (TIGIT)-CD28 switch receptor-modified T cells
have demonstrated superior antitumor function in a melanoma xenograft model [115]. Similar …

… A schematic overview of the immunosuppressive tumour microenvironment for chimeric
antigen receptor (CAR) T cells. CAR-T cells efficacy is hindered in the overall …

… genetically engineered T cells. T cells genetically equipped with chimeric antigen receptors
(… malignancies, although the efficacy of engineered T cells in treating solid tumors is far from …

… , tumor immunotherapy has become a new method of effectively treating tumors. Chimeric
antigen receptor (CAR) T cell … antibodies with the strong toxicity and persistence of cytotoxic …