Ratiometrically pH-insensitive upconversion nanoprobe: toward simultaneously quantifying organellar calcium and chloride and understanding the interaction of the …

C Ding, S Cheng, F Yuan, C Zhang, Y Xian - Analytical Chemistry, 2022 - ACS Publications
Fluorescence spectra and fluorescence lifetimes were … chloride calibration profile, the
perfusate and endosomal … indicate that it can be successfully used for measuring Cl – in vitro. …

Long-term quantitatively imaging intracellular chloride concentration using a core-/shell-structured nanosensor and time-domain dual-lifetime referencing method

L Ding, Y Lian, Z Lin, Z Zhang, X Wang - ACS sensors, 2020 - ACS Publications
… The Clindicator lucigenine is featured with its pH … fluorescence spectra of isCl with different
Clconcentrations. The … In order to accurately measure intracellular Clconcentration

Chloride transport across the lysosomal membrane

S Saha, A Blessing, TJ Jentsch - Ion and Molecule Transport …, 2020 - api.taylorfrancis.com
Chloride concentration in endosomes measured using a ratioable fluorescent Clindicator:
Evidence for chloride … Determinants of [Cl−] in recycling and late endosomes and Golgi …

Cl− and H+ coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltage-gated Cl−/H+ exchanger ClC-5

MH Chang, MR Brown, Y Liu, VG Gainullin… - Journal of Biological …, 2020 - ASBMB
endosomal acidification. Thus, an on-and-off “burst” of ClC-5 activity was crucial for preventing
Cl − exit from endosomes… -5, but the variant had a much slower Cl − and H + transport and …

Phagosomal chloride dynamics in the alveolar macrophage

V Riazanski, G Mauleon, AM Zimnicka, S Chen… - Iscience, 2022 - cell.com
… Relative levels of elemental chlorine (Cl) in hard X-ray fluorescenceChloride concentration
in endosomes measured using a ratioable fluorescent Cl- indicator: evidence for chloride

Engineering the ChlorON Series: Turn-On Fluorescent Protein Sensors for Imaging Labile Chloride in Living Cells

JN Tutol, WSY Ong, SM Phelps, W Peng… - ACS Central …, 2023 - ACS Publications
… by first measuring the fluorescence response of the variants to bromide at a pH of 8 using an
… ± 0.3 mM for Cl – ). (72) By relying on anion walking, we identified six variants with a turn-on …

Impaired endosome maturation mediates tubular proteinuria in dent disease cell culture and mouse models

KE Shipman, CJ Baty, KR Long, Y Rbaibi… - Journal of the …, 2023 - journals.lww.com
… of endosomal pH versus [Cl − ] in modulating endocytic traffic. … Alexa Fluor 647 fluorescence
intensity was quantified by … were incubated in buffers with chloride concentrations of 0, 25, …

Modulation of Lysosomal Cl Mediates Migration and Apoptosis through the TRPML1 as a Lysosomal Cl Sensor

D Lee, JH Hong - Cells, 2023 - mdpi.com
… In this study, we verified that reduced chloride levels acutely … [Cl − ] i was determined by
measuring MQAE fluorescence … , reduction of Clconcentration enhanced endosome Ca 2+ …

[PDF][PDF] Solute transport controls membrane tension and organellar volume

SR Chadwick, J Wu, SA Freeman - Cell Physiol. Biochem, 2021 - cellphysiolbiochem.com
… flux at the PM are unclear, measurements obtained from recycling endosomes for Cl- show a
ratioable fluorescent Cl- indicator: evidence for chloride accumulation during acidification. J …

Colorimetric and fluorescent turn-on detection of chloride ions with ionophore and BODIPY: Evaluation with nanospheres and cellulose paper

W Yang, J Zhai, J Li, Y Qin, Y Wu, Y Zhang, X Xie - Analytica Chimica Acta, 2021 - Elsevier
chloride sensitive nanospheres and paper-based chloridefluorescent chloride indicators,
the nanospheres exhibited Cl … the chloride ion concentrations were successfully measured