… (IKK) complex, a trimeric complex consisting of two kinases, IKK1 (IKKα) and IKK2 (IKKβ), and
… Our study reveals a critical role for IKK expression and activity for the long-term survival of …

… to a severe defect in ERK activation and memory CD8 T cell … the impaired ERK activation
in TRAF2-deficient CD8 T cells … activation in memory CD8 T cells, we isolated IKKα and IKKβ …

… is important for survival of mature and activated T cells and that … Impaired response of F5
Ikk2ΔTCD2 T cells to influenza … two serine/threonine kinases, IKK1 (IKKα) and IKK2 (IKKβ), and …

… , IKK1 (IKKα) and IKK2 (IKKβ), and a third regulatory … repressing cell death by inhibiting
the serine threonine kinase, … role for IKK expression and activity for long term survival of …

… T cells after leaving the thymus. This induction of IL-7R expression is, however, essential for
long-term survival of naive T cells ( … functional differentiation of SP thymocytes and T cells in …

… T cell development, tune the long-term survival of naïve T cells, guide the development
and function … The IKK complex, a trimeric complex of two kinases, IKK1 (IKKα) and IKK2 (IKKβ) …

… This study reveals that impaired IKKα expression or activity … Because reduced IKKα
expression or activity worsens survival … distribution between CD8 + T cell numbers and IKKα …

… reported that CD8 T cells uniquely impaired in triggering TCR… limit the generation of long-term
protective T cell memory and … to regulate CD8 T cell survival and CD8 T cell memory. In the …

… , cell activation and survival, and tissue remodeling. … , impaired T and B cell function,
virtual absence of mTECs, … kinase dead mutant do not exhibit organ infiltration by T cells, …

… > 98% of cells; surviving αβ T cells differentiate into CD4 + … impaired in TH17-polarized Rel
−/− T cells, as well as in … , display impaired upregulation of CXCR5, leading to a severe defect …