Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism

S Badawy, YQ Yang, Y Liu, MA Marawan… - Critical Reviews in …, 2021 - Taylor & Francis
… Approach to systematic review This review article provides an overview of the basic toxicology
… levels are thought to be the possible mechanisms of CIP neurotoxicity (Ilgin et al. Citation…

[HTML][HTML] An examination of the effect of rutin against neurotoxicity induced by ciprofloxacin antibiotic in wistar rats

AJ Al-Naely, HA Al-Hamadawi… - Archives of Razi …, 2022 - archrazi.areeo.ac.ir
… Almutairi, Alanazi ( 34 ) demonstrated that Rutin has beneficial effects and can reduce
cisplatin medicine neurotoxicity with possible mechanisms by its antioxidant nature. On the other …

Fumaric acid protects rats from ciprofloxacin-provoked depression through modulating TLR4, Nrf-2, and p190-rho GTP

MM Khalaf, HM Mahmoud, MA Kandeil… - Drug and Chemical …, 2024 - Taylor & Francis
evaluation of fumaric acid’s role in the control of p190-RhoGTP in a rat model of
ciprofloxacin-induced … putative neuroprotective mechanism of fumaric acid against …

Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4

A Salama, HAAH Mahmoud, MA Kandeil… - Immunopharmacology …, 2021 - Taylor & Francis
… The aim of the current study was to evaluate camphor possible neuroprotective effect against
… to be the possible mechanisms of ciprofloxacin-associated neurotoxicity and inflammation […

Protective Influence of Phyllanthus Muellarianus on Ciprofloxacin-Induced Neurotoxicity in Male Rats

OB Ibitoye, NO Aliyu, TO Ajiboye - Journal of Dietary Supplements, 2020 - Taylor & Francis
… leaf extract of Phyllanthus muellarianus on ciprofloxacin neurotoxicity in male rats. Control
rats (… muellarianus reversed ciprofloxacin-induced neurotoxicity by restoring ciprofloxacin-…

Long-term toxicity of fluoroquinolones: a comprehensive review

NHA Hussen, SH Qadir, HS Rahman… - Drug and Chemical …, 2024 - Taylor & Francis
… Therefore, we provide a summary of the molecular mechanisms responsible for the long-…
These results show that the association between structures of neurotoxicity and FQs is not well-…

Neurobehavioral impairments in ciprofloxacin-treated osteoarthritic adult rats.

G Kékesi, E Ducza, H Gálity, A Büki… - Clinical …, 2023 - search.ebscohost.com
… Fluoroquinoloneinduced neurotoxic adverse events have been reported in a few case …
preclinical studies have examined the mechanisms underlying the observed psychogenic effects. …

Synergistic effect of spermidine and ciprofloxacin against Alzheimer's disease in male rat via ferroptosis modulation

MAM Youssef, TM Mohamed, AA Bakry… - International Journal of …, 2024 - Elsevier
… This study investigated AD-related biomarkers like neurotoxic amyloid beta (Aβ), arginase
I, and … [68] elucidated the underlying mechanism, revealing SPD's ability to target histone …

[HTML][HTML] Depressive and other adverse CNS effects of fluoroquinolones

P Wierzbiński, J Hubska, M Henzler, B Kucharski… - Pharmaceuticals, 2023 - mdpi.com
… studies were further evaluated for key terms and relevance to the aims of the review. After …
Finally, further research is needed to confirm the underlying mechanisms of fluoroquinolone-…

[HTML][HTML] Effects of single and combined ciprofloxacin and lead treatments on zebrafish behavior, oxidative stress, and elements content

R Jijie, E Paduraru, IA Simionov, C Faggio… - International Journal of …, 2023 - mdpi.com
neurotoxicity has been rarely considered in risk assessment. … and in combination with
ciprofloxacin induced an oxidative stress … the mechanisms underlying single and joint toxic effects. …