Uncovering the Early Events Associated with Oligomeric Aβ-Induced Src Activation
SI Mota, L Fão, P Coelho, AC Rego - Antioxidants, 2023 - mdpi.com
… to the loss of synaptic plasticity and cellular demise [2]. … of 15-month-old 3xTg-AD female
mice, both occurring concomitantly … shown to rescue spatial memory deficits, synaptic depletion, …
mice, both occurring concomitantly … shown to rescue spatial memory deficits, synaptic depletion, …
[引用][C] Alzheimer's disease dementia risk in post-traumatic stress disorder: identification of common underlying mechanisms using rat models.
OS Faborode - 2021
Therapeutic potential of glutathione-enhancers in stress-related psychopathologies
I Zalachoras, F Hollis, E Ramos-Fernández… - Neuroscience & …, 2020 - Elsevier
… Glutathione (GSH) is arguably the most important endogenous antioxidant in the brain. In
recent years, aberrant GSH levels have been implicated in different psychiatric disorders, …
recent years, aberrant GSH levels have been implicated in different psychiatric disorders, …
ACNP 59th Annual Meeting: Poster Session III
T Hanania, M Varney, E Leahy, D Budac, E Dugan… - nature.com
… beta coherence during hits in 3xTG-AD mice is suggestive of … was blocked by the SERT
inhibitor citalopram (100 nM), indicating … stress (CUMS) in male and female mice, as it is a robust …
inhibitor citalopram (100 nM), indicating … stress (CUMS) in male and female mice, as it is a robust …
Refinement of Marble Burying Test to Model Behavioral and Neuropsychiatric Symptoms: Studies in Two Animal Models
ME Santana Santana - 2022 - tdx.cat
… of hippocampal AKT activity and ameliorated the contextual fear … we consider males and
females as two natural biological … in the second part of this thesis using the 3xTg-AD mice. …
females as two natural biological … in the second part of this thesis using the 3xTg-AD mice. …
Chronic Stress Induces Microglial-Mediated Inflammatory Responses and Compromises the Oligodendroglial & Neuronal Homeostases Leading to Depression
AG Kokkosis - 2021 - search.proquest.com
… -lineage (OLN) and neuronal deficits in a mouse model for depression. I utilized the … in
adult male mice. Behavioral tasks were performed to categorize the defeated mice to susceptible …
adult male mice. Behavioral tasks were performed to categorize the defeated mice to susceptible …
Impaired sleep is associated with tau deposition on 18F-flortaucipir PET and accelerated cognitive decline, accounting for medications that affect sleep
… axis, contributing to cognitive impairment via reduction in BDNF, an essential neurotrophin
for synaptic plasticity and memory consolidation. [14,91] Mouse models of AD have shown …
for synaptic plasticity and memory consolidation. [14,91] Mouse models of AD have shown …
Cure of alzheimer's dementia requires addressing all of the affected brain cell types
J Fessel - Journal of Clinical Medicine, 2023 - mdpi.com
… , and ameliorated brain demyelination [64]. It enriched synaptic genes [65], prevented synaptic
… Microglial activation was ameliorated by riluzole [168] which also upregulated the mRNA …
… Microglial activation was ameliorated by riluzole [168] which also upregulated the mRNA …
Alzheimer's disease: pathogenesis and therapeutic interventions
… NMDA receptors are vital in the control of synaptic plasticity and memory … For instance, high
doses of citalopram can result in alarming … This resulted in enhanced spatial memory in the …
doses of citalopram can result in alarming … This resulted in enhanced spatial memory in the …
Functional Significance of Cortical Cholinergic Circuits in Cognitive Decline in Mouse and Human
MR Ananth - 2019 - search.proquest.com
… thickness and volume and spatial memory task ………………… for heterosynaptic regulation
of synaptic plasticity 25. … perhaps ameliorate the memory impairments associated with …
of synaptic plasticity 25. … perhaps ameliorate the memory impairments associated with …