… Cleavage of polycystin-1 at its G protein coupled receptor … cleaved at its GPS site, and that
the N terminal domain that is … machinery required to mediate the GPS site cleavage resides …

… receptor of the egg jelly (REJ) domain. This study aims to examine the interaction of the REJ
domain of polycystin-1 … each other, requiring the presence of NCI domains. This interaction …

… polycystin 1 (PC1), a large membrane associated receptor-… kidney disease domain repeats;
REJ, receptor for egg jelly; … GAIN domain, but the products remain attached after cleavage by …

… at the REJ region affects GPS cleavage by disruption [10]. … obtained from the REJ domain
of polycystin-1 from the NCBCI-… N-terminal extracellular domain is required for polycystin-1-…

… , PC1, or Polycystin-1) with a long extracellular domain and has … to the sea urchin sperm
receptor for egg jelly [14]. This … segment that undergoes cleavage during normal processing and …

… receptor (GPCR) proteolytic cleavage site, or GPS, in its extracellular N-terminal domain …
-proximal region with homology to a sea urchin receptor for egg jelly (REJ) with a latrophilin-like …

… The polycystin-1 lipoxygenase and alpha toxin domain of … a ∼700-amino-acid receptor for
egg jelly (REJ) domain—a motif … The REJ domain is required for cleavage at the ∼40-residue …

… -protein-coupled receptor proteolysis site cleavage of polycystin-1 in renal physiology and …
Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human …

… domains are sufficient for its channel function. We also show that the cleavage of polycystin-1
… TJ, Zhou F, Germino GG (2002) Cleavage of polycystin-1 requires the receptor for egg jelly …

… Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by
human … and receptor for egg jelly (REJ) domain. PC1 CTF comprises 11 transmembrane (TM) …