… This review traces the development of targeted radionuclide therapy (TRT) (the Magic
Bullet) from the discovery of radioactivity in nature and the subsequent discovery of artificial …

… -targeting ligands labeled with radionuclides have been evaluated in several preclinical and
clinical … are three types of radiation that can be used for targeted radionuclide therapy: β − -…

… Radionuclide therapy has been employed frequently in the past several decades for … ,
curative therapy, and pain management applications [1]. Targeted radionuclide therapy (TRT) is …

… they can be successfully applied for both diagnostics and therapy. Effective application of
relevant radionuclides in pre-clinical and clinical studies depends on the choice of a sufficient …

… -efficient use in a clinical routine is feasible. Recent preclinical and clinical developments and
outline perspectives for the … Undeniably, targeted radionuclide therapy has demonstrated a …

… The demonstration of SSTRs in NET opened the door to targeted radionuclide therapy
based on the administration of synthetic analogs of somatostatin labeled with beta-emitting …

… antigen (PSMA) receptor targeting agents, and a number of peptide-derived
radiopharmaceuticals. Additionally, these recent technological developments, combined with new …

… , its clinical merits in current treatment and future perspectives. We will highlight different
radionuclides … peptide-conjugates that hold these radionuclides. We will zoom in on the latest …

… of the general concept of targeted radionuclide therapy (TRT) gathering several promising
methods such as peptide receptor radionuclide therapy (PRRT) or radioimmunotherapy (RIT) …

… for low LET radiation. Radiobiological characterization of targeted radionuclide therapy has
… This opens an opportunity for α radiation therapy labeled to PSMA ligands. Kratochwil et al. …