… cancer predisposition in all patients with advanced cancer and (2) use of integrative genomic
… testing in patients with advanced cancer 8 -16 report a wide range of clinically actionable …

… Our study did not evaluate treatment response, inclusive of possible somatic genomic
biomarkers of response; however, such studies are currently being conducted in specific …

… Here, we discuss ongoing efforts to enhance the clinical utility of tumour genomic …
therapy response. We also discuss the potential clinical utility of more comprehensive whole-genome …

… guidance on using genomic sequencing to inform treatment selection for patients with
metastatic or advanced solid tumors. The neoadjuvant and adjuvant treatment settings were …

… Cancer progression is driven in part by genomic alterations 1 . The genomic characterization
of cancers … that generation of genomic profiling in patients with cancer could allow the …

… oncology nurses and tumor registrars, with oncologist oversight) who followed prespecified,
… part of clinical care, was included in this study given previous associations with outcomes in …

… We assessed a real-world clinico-genomic database to determine clinical outcomes to
matched targeted therapy after detection of a targetable GA using liquid biopsy or tissue CGP. …

… for clinical care, we trained our model on prospective genomic data from 7791 patients with
advanced cancer… co-occurrence of genomic features across all tumor types. The probabilistic …

… In recent years, several clinical guidelines have endorsed genomic testing for certain …
physicians to inform treatment decision-making and hence focus on clinical and patient outcomes. …

… Our data offer a rich resource for investigation of advanced cancers and interpretation of
whole-genome and transcriptome sequencing in the context of a cancer clinic. …