… Discovery of estrogen and progestin compound (in orange) - marketing authorization for …
is not a coagulation protein and other biological variables better reflecting the impact of COCs …

… biology, until his tragic death by suicide in 1932.[2] … an unbalance between blood coagulation
activity and its negative … had to realize that third-generation progestins were associated …

… on third generation OCs as … blood clotting disorders, family history of DVT/PE, obesity,
surgical procedures or injuries, pregnancy and especially the use of oral contraceptive (OC) pills …

… , coagulation and blood pressure. In order to compare the effect of combined … clinical
implications of these changes are unknown. Finally, prothombotic effects of third-generation pills …

… of users compared to those on third-generation pills, in 2001, … , which is what determines the
biologic activity of the steroids. … In COC users minimal increases of coagulation factors (such …

… EE, E 2 , and E 4 exert their biologic effects via interactions … involving the effects of EE, E 2 ,
and E 4 on the coagulation and … changes in hemostatic factors and the clinical finding of VTE. …

… Since the 1960s, inherited coagulation disorders have been identified which predispose to
a … Third generation oral contraceptives and risk of venous thrombosis: meta-analysis. BMJ …

… This finding has led to the search for novel estrogens, with … has fewer adverse effects
on blood biological coagulation, … in COCs containing third-generation progestogens (containing …

… in coagulation parameters, thus conditioning many biological … coagulation and
fibrinolysis (Figure 2). These modifications are more pronounced in women taking the third-generation …

… of a progestin molecule on coagulation: glucocorticoid, anti-… to biologically explain many of
the advantages found with the use of NGM in the clinical practice as a hormonal contraceptive…