HPLC-MS-MS analysis of thyroid hormones and iodotyrosines in knocked-out murine and natural human DEHAL-1 deficiency.
M Borsò - 2021 - usiena-air.unisi.it
… of the Iodotyrosine Dehalogenase-1 (DEHAL-1) enzyme. Mono-iodotyrosine (MIT) and di-iodotyrosine
(… Three isoforms of this enzyme were identified, namely DEHAL-1, DEHAL-1B and …
(… Three isoforms of this enzyme were identified, namely DEHAL-1, DEHAL-1B and …
Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine deiodinase
JH Olker, JJ Korte, JT Haselman, MW Hornung… - Aquatic Toxicology, 2022 - Elsevier
… enzyme iodotyrosine deiodinase (dehalogenase, IYD). IYD has an important role in
maintaining thyroid function through conservation of iodide, which is a crucial micronutrient for …
maintaining thyroid function through conservation of iodide, which is a crucial micronutrient for …
In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase
JH Olker, JJ Korte, JS Denny, JT Haselman, PC Hartig… - Toxicology in Vitro, 2021 - Elsevier
… has been documented in humans, rodents, and amphibians. First documented in humans,
failure of IYD (named DEHAL1) due to genetic mutations resulted in hypothyroidism, goiter, …
failure of IYD (named DEHAL1) due to genetic mutations resulted in hypothyroidism, goiter, …
The role of thyroglobulin in thyroid hormonogenesis
CE Citterio, HM Targovnik, P Arvan - Nature Reviews Endocrinology, 2019 - nature.com
… also yields a large supply of uncoupled iodotyrosines. MIT and DIT can be released into the
… by iodotyrosine dehalogenase 1 (also known as IYD1) before they escape from the thyroid …
… by iodotyrosine dehalogenase 1 (also known as IYD1) before they escape from the thyroid …