… Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high-level E. maxima challenge in a broiler model of coccidiosis

I Pastor-Fernández, S Kim, V Marugán-Hernández… - Parasites & …, 2020 - Springer
… We also measured IL-10 levels in the intestine since this … protective immune responses in
vaccinated chickens after high-level … modifies host immune responses against heterologous E. …

An Eimeria maxima Antigen: Its Functions on Stimulating Th1 Cytokines and Protective Efficacy Against Coccidiosis

C Chen, Y Zhang, J Liu, M Wang, M Lu, L Xu… - Frontiers in …, 2022 - frontiersin.org
… an effective immune response against coccidiosis. However, … observe significantly increased
levels of IL-10 and TGF-β in … output of the chickens infected by Eimeria maxima. The ACIs of …

Characterization of vaccine-induced immune responses against coccidiosis in broiler chickens

C Gaghan, D Adams, J Mohammed, R Crespo… - Vaccine, 2022 - Elsevier
… species (Eimeria acervulina, Eimeria maxima, EimeriaIL-10 transcription in the spleen at
pre-challenge, while a post-challenge increase in the cecal tonsils in the vaccinated chickens. …

Kinetics of the Cellular and Transcriptomic Response to Eimeria maxima in Relatively Resistant and Susceptible Chicken Lines

A Bremner, S Kim, KM Morris, MJ Nolan… - Frontiers in …, 2021 - frontiersin.org
… We also found that IFN-γ and IL-10 protein expression and … parasitemia and serum IL-10 in
line 15I chickens. Furthermore, … IL-10 reduces the efficacy of the immune response to Eimeria

[HTML][HTML] Recombinant ubiquitin-conjugating enzyme of Eimeria maxima induces immunogenic maturation in chicken splenic-derived dendritic cells and drives Th1 …

SA Lakho, M Haseeb, J Huang, MW Hasan… - Microbial …, 2020 - Elsevier
It is considered that T cell-mediated immunity is the key mediator of immune response against
Eimeria infections [… Our results demonstrated that the secretion of TGF-β and IL-10 was not …

[HTML][HTML] Molecular characterization and immune protective efficacy of 3 Eimeria tenella antigens

L Zhang, Z Song, P Li, X Song, X Tang, D Hu - Poultry Science, 2024 - Elsevier
… Our results suggest that rEten5-B induces host IFN-γ and IL-10maxima found that the
increased expression of IFN-γ and … To characterize the host immune response to these antigens, …

[HTML][HTML] In vitro effects of 5 recombinant antigens of Eimeria maxima on maturation, differentiation, and immunogenic functions of dendritic cells derived from chicken …

M Haseeb, SA Lakho, J Huang, MW Hasan… - Poultry science, 2020 - Elsevier
functions of chicken splenic derived DCs more efficiently, which might represent an effective
molecule for inducing the host Th1-mediated immune response against Eimeria … that IL-10

[HTML][HTML] Dietary supplementation with anti–IL-10 antibody during a severe Eimeria challenge in broiler chickens

MSA Rasheed, UP Tiwari, ML Oelschlager, BN Smith… - Poultry science, 2020 - Elsevier
… of the host immune response by Eimeriahost IL-10 activity by egg anti–IL-10 antibody may
elicit an intense proinflammatory reaction and eliminate the parasite during a severe Eimeria

Kinetics of the immune response to Eimeria maxima in relatively resistant and susceptible chicken lines

A Bremner, S Kim, K Morris, MJ Nolan, D Borowska… - bioRxiv, 2019 - biorxiv.org
… During the characterization of biological roles of chicken IL-10, its potential role as a biomarker
for Eimeria spp. infection was suggested. Increased IL10 mRNA levels were observed in …

[HTML][HTML] IFN-γ inhibitory molecules derived from Eimeria maxima inhibit IL-12 secretion by modulating MAPK pathways in chicken macrophages

C Chen, Y Chen, M Lu, L Xu, R Yan, X Li, X Song - Poultry Science, 2024 - Elsevier
… Regarding avian coccidiosis, IL-10 is thought to have a pivotal role in aiding the parasite
in evading the host immune response. Studies showed that single or mixed infections of …