[HTML][HTML] Ligand entry into fatty acid binding protein via local unfolding instead of gap widening

T Xiao, Y Lu, J Fan, D Yang - Biophysical journal, 2020 - cell.com
Coexistence of multiple minor states of fatty acid binding protein and their functional
relevance… To examine if this partial unfolding process is relevant to the uptake of fatty acids, we …

[HTML][HTML] The observation of ligand-binding-relevant open states of fatty acid binding protein by molecular dynamics simulations and a Markov state model

Y Guo, M Duan, M Yang - International journal of molecular sciences, 2019 - mdpi.com
… ligand association rate in the native closed state [15], are “… several minor states of human
intestinal fatty acid binding … that these states are irrelevant to the function of fatty acid transport …

Intestinal fatty acid binding protein: A rising therapeutic target in lipid metabolism

X Huang, Y Zhou, Y Sun, Q Wang - Progress in Lipid Research, 2022 - Elsevier
… activity of relevant enzymes. In addition, FABP2 is a transport … The second puzzle is why
FABP1 and FABP2 coexist in the … as the main fatty acid-binding protein in the small intestine. …

Does intrinsic disorder in proteins favor their interaction with lipids?

E Deryusheva, E Nemashkalova, M Galloux… - …, 2019 - Wiley Online Library
… in this study possess fatty acidbinding properties, IDPs should … Due to the coexistence of
multiple phases of lipids under … of the content of lipid-binding proteins among DisProt entries (…

[PDF][PDF] Serum fatty acid binding proteins as a potential biomarker in atrial fibrillation.

K Golaszewska, E Harasim-Symbor… - Journal of Physiology …, 2019 - jpp.krakow.pl
… , diabetes and coexisting disorders including cardiovascular … current data on the clinical
significance of FABPs in terms of … FABPs are small cytoplasmic proteins with molecular mass …

[HTML][HTML] Effects of ligand binding on the energy landscape of Acyl-CoA-binding protein

P Sonar, L Bellucci, A Mossa, PO Heidarsson… - Biophysical …, 2020 - cell.com
… discussion on the functional significance of the conformational … specific ligand-protein
interactions and minor or extensive … for fatty acid chain elongation and sphingolipid synthesis ( …

Low membrane fluidity triggers lipid phase separation and protein segregation in living bacteria

M Gohrbandt, A Lipski, JW Grimshaw… - The EMBO …, 2022 - embopress.org
… Here, the coexistence of fluid liquid‐disordered and liquid‐… To confirm that changes in fatty
acid composition translate to … of DNA‐binding protein HBsu (top), cell division protein FtsZ (…

Preferential protein partitioning in biological membrane with coexisting liquid ordered and liquid disordered phase behavior: underlying design principles

J Bodosa, SS Iyer, A Srivastava - The Journal of Membrane Biology, 2020 - Springer
Small rafts can sometimes be stabilized to form larger … phases and we will also discuss the
functional relevance of … Investigation of oligomeric state of TCR partitioning into lipid domain …

Molecular mechanisms for biosynthesis and assembly of nutritionally important very long chain polyunsaturated fatty acids in microorganisms

X Qiu, X Xie, D Meesapyodsuk - Progress in Lipid Research, 2020 - Elsevier
… PPAR), and sterol regulatory element binding protein (SREBP) [6,… the major fatty acids in
cortical gray matter, the functional part … In type II or type I fatty acid synthesis, a single small ACP, …

[HTML][HTML] Heart-type fatty acid-binding protein (H-FABP) and its role as a biomarker in heart failure: what do we know so far?

R Rezar, P Jirak, M Gschwandtner, R Derler… - Journal of clinical …, 2020 - mdpi.com
… The small cytoplasmic heart-type fatty acid-binding protein (H… Manuscripts that appeared
relevant were read in full text. … As the coexistence of HF and chronic kidney disease is …