Colistin monotherapy versus combination therapy for carbapenem-resistant organisms

KS Kaye, D Marchaim, V Thamlikitkul, Y Carmeli… - NEJM …, 2022 - evidence.nejm.org
colistin be combined with a carbapenem for the treatment of infections caused by
carbapenem-resistant … therapy with colistin and either rifampin 18,19 or fosfomycin 20 for invasive …

Colistin Plus Carbapenem versus Colistin Monotherapy in the Treatment of Carbapenem-Resistant Acinetobacter baumannii Pneumonia

HJ Shi, JS Lee, SY Park, Y Ko… - Infection and drug …, 2019 - Taylor & Francis
… Several observational studies showed uniformly lower mortality for combination therapy
than for carbapenem-resistant or carbapenemase-producing K. pneumoniae compared with …

[HTML][HTML] In-Vitro Evaluation of Different Antimicrobial Combinations with and without Colistin Against Carbapenem-Resistant Acinetobacter Baumannii

A Oliva, S Garzoli, M De Angelis, C Marzuillo, V Vullo… - Molecules, 2019 - mdpi.com
Carbapenem-resistant Acinetobacter baumannii (CR-Ab) infections are associated with high
morbidity and mortality. The aim of the study was to evaluate the in-vitro activity of different …

Dose-dependent synergistic interactions of colistin with rifampin, meropenem, and tigecycline against carbapenem-resistant Klebsiella pneumoniae biofilms

A Geladari, M Simitsopoulou… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… activity of these drug combinations against carbapenem-resistant K. pneumoniae biofilms. …
, rifampin and colistin alone significantly damage biofilms of carbapenem-resistant K. …

[HTML][HTML] … activity of a combination of meropenem, colistin, tigecycline, rifampin, and ceftolozane/tazobactam against carbapenem-resistant Acinetobacter baumannii

YG Ju, HJ Lee, HS Yim, MG Lee, JW Sohn, YK Yoon - Scientific reports, 2022 - nature.com
combinations against carbapenem-resistant Acinetobacter baumannii (CRAB) isolates. The
in vitro activity of six two-drug combinations … two-drug combinations against CRAB isolates. …

[HTML][HTML] … of Loading Dose Colistin–Meropenem versus Loading Dose Colistin–Imipenem in the Treatment of Carbapenem-Resistant Acinetobacter baumannii …

W Katip, P Oberdorfer, N Kasatpibal - Pharmaceutics, 2022 - mdpi.com
… that combinations of LD colistin and meropenem should be considered when treating CRAB
… ’s synergy with a variety of antibiotics, including imipenem, meropenem, rifampin, fosfomycin…

[HTML][HTML] Effectiveness of colistin with rifampicin and meropenem against colistin-resistant Acinetobacter baumannii strains: An in vitro study

A Mosca, L Dalfino, F Romanelli… - …, 2020 - pharmacophorejournal.com
… of colistin for the treatment of carbapenem-resistant Acinetobacter baumannii infections has
led to the emergence of colistin … of colistin/rifampicin and colistin/meropenem combinations

The efficacy of colistin monotherapy versus combination therapy with other antimicrobials against carbapenem-resistant Acinetobacter baumannii ST2 isolates

J Li, Y Fu, J Zhang, Y Zhao, X Fan, L Yu… - Journal of …, 2020 - Taylor & Francis
… the efficacy of colistin both alone and in combination with either … The combination of colistin
and meropenem displayed the … , while the colistin-levofloxacin combination showed a higher …

[HTML][HTML] Systematic review and meta-analysis of in vitro efficacy of antibiotic combination therapy against carbapenem-resistant Gram-negative bacilli

L Scudeller, E Righi, M Chiamenti, D Bragantini… - International journal of …, 2021 - Elsevier
colistin/imipenem [71] and colistin/doripenem [96]. These results were not confirmed for
combination of colistin … 0.91 were confirmed for colistin and rifampicin combination both in PK/PK …

[HTML][HTML] Effectiveness of Colistin in carbapenem resistant Acinetobacter baumannii–A Systematic Review

F Ahmed, MT Mahmud, S Naher, MJ Rana, R Ara… - Health Sciences …, 2023 - Elsevier
… is administered in all included articles, and in two studies, other antibiotics such as
tigecycline, minocycline, carbapenem, rifampin, and sulbactam are used in combination with …