Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies

J McLaughlin, S Watterson, AM Layton, AJ Bjourson… - Microorganisms, 2019 - mdpi.com
… [78] using a whole genome microarray derived from strain KPA171202 (type IB). After
growth in brain heart infusion broth (BHI), comparison of the KPA171202 transcriptome with the …

Comparative Genomic Analyses and CRISPR-Cas Characterization of Cutibacterium acnes Provide Insights Into Genetic Diversity and Typing Applications

N Cobian, A Garlet, C Hidalgo-Cantabrana… - Frontiers in …, 2021 - frontiersin.org
… Originally classified and named as Propionibacterium acnes, it was recently reclassified as
… Besides genomic content, transcriptomic and proteomics analyses of virulence factors should …

Comparative Genomic Analysis of Cutibacterium spp. Isolates in Implant-Associated Infections

…, K Strašek Smrdel, T Triglav, P Maver Vodičar - Microorganisms, 2023 - mdpi.com
… Therefore, the aim of this study was to perform an in silico comparative genomic analysis
of 64 Cutibacterium spp. isolates from confirmed or suspected IAIs showing different clinical …

Transcriptomic analysis of the antimicrobial activity of prodigiosin against Cutibacterium acnes

HJ Kim, MS Lee, SK Jeong, SJ Lee - Scientific Reports, 2023 - nature.com
acnes strain, an opportunistic pathogen, was then treated with prodigiosin, and the antibacterial
mechanism of prodigiosin was studied through transcriptomic … Our transcriptome data …

[HTML][HTML] Proteomic and transcriptomic analyses of Cutibacterium acnes biofilms and planktonic cultures in presence of epinephrine

AV Gannesen, MI Schelkunov, RH Ziganshin… - AIMS …, 2024 - aimspress.com
Transcriptomic and proteomic analysis were performed on 72 h biofilms of the acneic strain
Cutibacterium acnes … No correlation was found between proteomic and transcriptomic profiles…

Multi-omics signatures reveal genomic and functional heterogeneity of Cutibacterium acnes in normal and diseased skin

T Yu, X Xu, Y Liu, X Wang, S Wu, Z Qiu, X Liu, X Pan… - Cell Host & Microbe, 2024 - cell.com
… -strain genome, transcriptome, and … B Genome assembly and quality filtering B Pan-genome
and phylogenetic analysis B Characterization of C. acnes strains B Comparative genomic

[HTML][HTML] Comparative Transcriptome Analysis of Acne vulgaris, Rosacea, and Hidradenitis Suppurativa Supports High Dose Dietary Zinc as a Therapeutic Agent

L Li, I Hajam, JS McGee, Z Tang, Y Zhang, N Badey… - Medrxiv, 2023 - ncbi.nlm.nih.gov
… In this report, we present a comparative analysis of transcriptomic data across these three
… ‘Propionibacterium acnes–induced immunopathology correlates with health and disease …

Transcriptomics analysis indicates trifarotene reverses acne-related gene expression changes

B Dreno, R Chavda, V Julia, A Khammari… - Frontiers in …, 2021 - frontiersin.org
… The aim of the current transcriptomic analysis was to identify the gene expression signatures
in acne papules as well as elucidate the pathways that are modulated during papule …

Genome-scale metabolic modeling and in silico analysis of opportunistic skin pathogen Cutibacterium acnes

SK Kim, M Lee, YQ Lee, HJ Lee, M Rho… - Frontiers in Cellular …, 2023 - frontiersin.org
… Thus, we conducted comparative genomic analysis (see Material and Methods), resulting in
a total of 1,467 genes identified as core genes present in all the strains, and 58, 16, and 1 RT…

[HTML][HTML] Integrative network pharmacology and transcriptomics analysis reveal the mechanism of Tanreqing in the treatment of acne vulgaris

X Ren, N Zhou, D Li, J Yang, Y Wang, G He, S Ma… - Phytomedicine Plus, 2024 - Elsevier
… For example, Propionibacterium acnes often develops resistance to topical antibiotics such
as clindamycin and erythromycin, and its resistance to newer macrolide antibiotics such as …