Genomics of antibiotic‐resistance prediction in Pseudomonas aeruginosa

J Jeukens, L Freschi, I Kukavica‐Ibrulj… - Annals of the New …, 2019 - Wiley Online Library
… The challenge of this approach will be to take the genomicComparative genomics
approaches have identified changes … contains a mixture of both drug-resistant and drug-susceptible …

[PDF][PDF] A panel of diverse Pseudomonas aeruginosa clinical isolates for research and development

…, E Lesho, JW Bennett, P McGann - JAC-antimicrobial …, 2021 - academic.oup.com
… The challenges posed by these formidable intrinsic … aeruginosa isolates housed at the
Multi-drug resistant organism … Comparison of Pseudomonas aeruginosa strains reveals …

[HTML][HTML] Comparative genomics of ocular Pseudomonas aeruginosa strains from keratitis patients with different clinical outcomes

K Kandasamy, K Thirumalmuthu, NV Prajna, P Lalitha… - Genomics, 2020 - Elsevier
… Indeed, multiple drug-resistant (MDR) strains carrying exoU protein … -genome sequenced
and annotated genomes of five P. aeruginosa ocular strains compared to reference genome

Pseudomonas aeruginosa: a clinical and genomics update

…, C Mirande, A Oliver, P Moons… - FEMS Microbiology …, 2021 - academic.oup.com
Pseudomonas aeruginosa causes a wide variety of … genes rendering them multi-drug
resistant (MDR) and particularly … (Pa-BSI) are a most serious issue and a challenge when AMR …

Genomic heterogeneity underlies multidrug resistance in Pseudomonas aeruginosa: A population-level analysis beyond susceptibility testing

LJ Rojas, M Yasmin, J Benjamino, SM Marshall… - PloS one, 2022 - journals.plos.org
… Our findings challenge the applicability of antimicrobial stewardship programs based on …
identified by comparison of primary sequence reads to the PA1RG reference genome using the …

Comparative genomics analysis of Acinetobacter baumannii multi-drug resistant and drug sensitive strains in China

JF Dong, C Feng, P Wang, RQ Li, QH Zou - Microbial Pathogenesis, 2022 - Elsevier
… has posed a major challenge for clinical treatment. There is … the genomes of 10 drug sensitive
and 10 multi-drug resistant … from other genera like Pseudomonas aeruginosa or Klebsiella …

[HTML][HTML] Genomic analysis of an extensively drug-resistant Pseudomonas aeruginosa ST312 harbouring IncU plasmid-mediated blaKPC-2 isolated from ascitic fluid

DC Tartari, CP Zamparette, G Martini… - Journal of Global …, 2021 - Elsevier
genome might be useful for comparative genomic analyses to monitor the spread of
plasmid-mediated bla KPC in P… report the genomic features of an extensively drug-resistant (XDR) …

[HTML][HTML] Unveiling a high-risk epidemic clone (ST 357) of 'Difficult to Treat Extensively Drug-Resistant'(DT-XDR) Pseudomonas aeruginosa from a burn patient in …

SM Mondol, MR Islam, NN Rakhi, SK Shakil… - Journal of Global …, 2024 - Elsevier
… in addressing the urgent challenges posed by MDR (Multidrug-Resistant), XDR (Extensively …
Pangenome and comparative genome analysis Pangenome and comparative genome

Susceptibility profiles and resistance genomics of Pseudomonas aeruginosa isolates from European ICUs participating in the ASPIRE-ICU trial

G Torrens, TE van der Schalk… - Journal of …, 2022 - academic.oup.com
… and particularly XDR Pseudomonas aeruginosa strains is … Comparative analysis of
susceptibility profiles between paired PAS and respiratory samples from 45 patients. (b) Comparative

Comparative genomics of antibiotic-resistant uropathogens implicates three routes for recurrence of urinary tract infections

R Thänert, KA Reske, T Hink, MA Wallace, B Wang… - MBio, 2019 - Am Soc Microbiol
… IMPORTANCE The increasing antimicrobial resistance of uropathogens is challenging
the … Here, we integrate genomic surveillance with clinical microbiology to show that drug-resistant