[HTML][HTML] A comparative study on erlotinib & gefitinib therapy in non-small cell lung carcinoma patients

P Thomas, B Vincent, C George… - Indian Journal of …, 2019 - journals.lww.com
Adverse drug reaction of both erlotinib (n=37) and gefitinib (n=34) … Terminology Criteria for
Adverse Events grading system. … erlotinib and gefitinib had similar effectiveness but gefitinib

[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib

Y Kim, SH Lee, JS Ahn, MJ Ahn, K Park… - Cancer Research and …, 2019 - ncbi.nlm.nih.gov
… with more efficient management of adverse events may in part … 3 or 4 adverse events for
afatinib, gefitinib, and erlotinib were … gefitinib and erlotinib have both demonstrated efficacy for …

[HTML][HTML] Comparison of effectiveness of Gefitinib, Erlotinib, and Afatinib in advanced non-small cell lung cancer patients with EGFR mutation positive in Indonesian …

N Sutandyo, A Hanafi, M Jayusman - Chinese journal of lung …, 2019 - ncbi.nlm.nih.gov
… to compare the effectiveness of first line TKIs; gefitinib, erlotinib, and afatinib in the treatment
of advanced stage NSCLC patientsadverse event and fatal adverse event in afatinib group …

[HTML][HTML] The different central nervous system efficacy among gefitinib, erlotinib and afatinib in patients with epidermal growth factor receptor mutation-positive non …

HA Jung, SY Woo, SH Lee, JS Ahn… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
… Although these limitations exist, our study is the largest comparing CNS efficacy between
first- … Because a prospective study comparing CNS efficacy between first- or second-generation …

[HTML][HTML] Efficacy and tolerability of erlotinib 100 mg/d vs. gefitinib 250 mg/d in EGFR-mutated advanced non-small cell lung cancer (E100VG250): an open-label …

S Zhao, Z Zhang, W Fang, Y Zhang, Z Zhang… - Frontiers in …, 2020 - frontiersin.org
adverse events. No significant difference was observed in the incidence of adverse events
of any grade or adverse events of grade 3–4 between erlotinib and gefitinib. Numerically, …

[HTML][HTML] Comparison of first-generation EGFR-TKIs (gefitinib, erlotinib, and icotinib) as adjuvant therapy in resected NSCLC patients with sensitive EGFR mutations

Q He, J Liu, X Cai, M He, C Li, H Liang… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
compare the efficacy among three first-generation EGFR-TKIs as adjuvant treatment and the
recurrence pattern in patients … had a similar detrimental effect in patients with stage IA stage …

Survival benefits from afatinib compared with gefitinib and erlotinib among patients with common EGFR mutation in first‐line setting

WC Kwok, JCM Ho, TCC Tam, MSM Ip… - Thoracic …, 2022 - Wiley Online Library
… these three EGFR-TKIs (gefitinib, erlotinib and afatinib), have different efficacy in … adverse
effects and grade 3 gastrointestinal adverse effects than those on first-line gefitinib and erlotinib

[HTML][HTML] A phase III, randomized, open-label study of ASP8273 versus erlotinib or gefitinib in patients with advanced stage IIIB/IV non-small-cell lung cancer

RJ Kelly, FA Shepherd, A Krivoshik, F Jie, L Horn - Annals of Oncology, 2019 - Elsevier
… incidence of these adverse events would compare with patients receiving erlotinib/gefitinib
[8, … Based on data showing limited efficacy and excessive toxicity versus the erlotinib/gefitinib

[HTML][HTML] Effectiveness and safety of afatinib, gefitinib, and erlotinib for treatment-naïve elderly patients with epidermal growth factor receptor-mutated advanced non …

LJ Hung, PC Hsu, CT Yang, CHS Kuo… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
… However, grade ≥3 adverse events, including skin toxicities, paronychia, mucositis, and …
However, afatinib remained the TKI of choice for older patients compared to erlotinib or gefitinib

[HTML][HTML] Patient-reported outcomes from FLAURA: osimertinib versus erlotinib or gefitinib in patients with EGFR-mutated advanced non-small-cell lung cancer

NB Leighl, N Karaseva, K Nakagawa, BC Cho… - European Journal of …, 2020 - Elsevier
… significantly improved PFS compared with erlotinib or gefitinib (18.9 … Rates for adverse
events were lower with osimertinib than … superior efficacy to erlotinib or gefitinib in patients with …