Foot-and-mouth disease vaccines: recent updates and future perspectives

M Kamel, A El-Sayed, H Castañeda Vazquez - Archives of virology, 2019 - Springer
… through vaccination with inactivated vaccines. These … vaccines are considered to be more
stable than previous … A trial was conducted recently to compare the immune response to this …

… (BEI) inactivation procedure for biosafety treatment of foot-and-mouth disease viruses (FMDV), vesicular stomatitis viruses (VSV), and swine vesicular disease virus  …

P Wu, YY Rodríguez, BJ Hershey, Y Tadassa… - Veterinary …, 2021 - Elsevier
inactivation agent for FMDV vaccine preparation due to its … multiple comparison revealed
the highest inactivation rate was … The antigenicity, quantity, and stability of 140S particles after …

Four simple biomimetic mineralization methods to improve the thermostability and immunogenicity of virus-like particles as a vaccine against foot-and-Mouth disease

M Guo, J Li, Z Teng, M Ren, H Dong, Y Zhang, J Ru… - Vaccines, 2021 - mdpi.com
… the method to treat FMD, the use of inactivated vaccines is … VLPs were increased compared
to those of the native VLPs. … showed that the thermal stability of biomineralized VLPs was …

Advances in novel vaccines for foot and mouth disease: focus on recombinant empty capsids

AC Mignaqui, V Ruiz, Y Durocher… - Critical reviews in …, 2019 - Taylor & Francis
… Current inactivated foot and mouth disease virus vaccine … , with CsCl gradient centrifugation
being the main technique … This difference could be related to stability issues of the empty …

Development of a potent stabilizer for long-term storage of foot-and-mouth disease vaccine antigens

AY Kim, H Kim, SY Park, SH Park, JS Kim, JW Park… - Vaccines, 2021 - mdpi.com
instability compared to other candidate vaccine strains. Based … The FMD vaccine is mainly
comprised of inactivated virus … for its instability [14], the 146S antigen stabilization technique

Calcium Chloride as a Novel Stabilizer for Foot-and-Mouth Disease Virus and Its Application in the Vaccine Formulation

JS Jin, G Lee, JY Kim, SA Lee, JH Park, SY Park, YJ Ko - Vaccines, 2024 - mdpi.com
virus is difficult to utilize as a vaccine given its low stability … Initially, serum samples were
inactivated at 56 C for 30 min before … virus is much more easily degraded at 45 C compared to …

Thermostability of the foot-and-mouth disease virus capsid is modulated by lethal and viability-restoring compensatory amino acid substitutions

S López-Argüello, V Rincón… - Journal of …, 2019 - Am Soc Microbiol
… thermal stability and instability in the capsid of foot-and-mouth … Current FMD vaccines are
based on chemically inactivated … Finally, we compared, as described in Materials and Methods

Sequence analysis of egyptian foot-and-mouth disease virus field and vaccine strains: intertypic recombination and evidence for accidental release of virulent virus

S Abd El Rahman, B Hoffmann, R Karam… - Viruses, 2020 - mdpi.com
vaccination programs with polyvalent inactivated vaccines, … For comparison, another
commercial inactivated FMD vaccine … The consensus 1D sequence of sample 10 was stable over …

[HTML][HTML] Vaccine induced immune response against foot and mouth disease virus in mithun (Bos frontalis)

H Lalzampuia, L Sunitibala Devi… - Journal of Veterinary …, 2022 - vetsci.org
vaccination using trivalent inactivated oil adjuvanted vaccine. … in different groups of vaccinated
mithun were compared after … Moreover, different serotypes have different stability [23], as …

Infection and protection responses of deletion mutants of non-structural proteins of foot-and-mouth disease virus serotype Asia1 in guinea pigs

H Lalzampuia, S Elango, JK Biswal… - Applied Microbiology …, 2022 - Springer
… , the viable virus was rescued, and the genetic stability of the … kinetics of the mutant viruses
were compared with that of … to inactivated antigens of foot-and-mouth disease virus (FMDV) …