[HTML][HTML] Outcome differences between first-and second-generation EGFR inhibitors in advanced EGFR mutated NSCLC in a large population-based cohort

SC Lau, N Chooback, C Ho, B Melosky - Clinical Lung Cancer, 2019 - Elsevier
… with advanced nonsmall-cell lung cancer who initiated … from EGFR TKIs, whereas the efficacy
is less certain in the patients … -, or third-line setting following cytotoxic chemotherapy were …

Cost-effectiveness of osimertinib as a second-line treatment in patients with EGFR-mutated advanced nonsmall cell lung cancer in China

H Guan, G Liu, F Xie, Y Sheng, L Shi - Clinical Therapeutics, 2019 - Elsevier
… as gefitinib, erlotinib, and icotinib, are the standard first-line … Lung Cancer), 3 was conducted
to compare the efficacy and … pattern of third-line therapy in patients with advanced NSCLC …

[HTML][HTML] Comparative clinical outcomes for patients with advanced NSCLC harboring EGFR exon 20 insertion mutations and common EGFR mutations

L Bazhenova, A Minchom, S Viteri, JM Bauml, SHI Ou… - Lung Cancer, 2021 - Elsevier
Non-small cell lung cancer … , and the available information on treatment efficacy is relatively
sparse due to the … In the second- and third-line setting, several different therapies were used, …

[HTML][HTML] Fruquintinib with gefitinib as first-line therapy in patients carrying EGFR mutations with advanced non-small cell lung cancer: a single-arm, phase II study

S Lu, JY Zhou, XM Niu, JY Zhou, H Jian… - … Lung Cancer …, 2021 - ncbi.nlm.nih.gov
… for third-line treatment of patients with metastatic colorectal … study, offers superior efficacy
compared to monotherapy, is … benefit for erlotinib users was superior, compared to gefitinib, and …

Erlotinib for NonSmall Cell Lung Cancer with Leptomeningeal Metastases: A Phase II Study (LOGIK1101)

K Nosaki, T Yamanaka, A Hamada, Y Shiraishi… - The …, 2020 - academic.oup.com
… This phase II trial evaluated the efficacy of erlotinib for patients with nonsmall cell lung
Togashi et al. have also compared gefitinib and erlotinib in terms of mean CSF concentration (8.2 …

Comparison of epidermal growth factor receptor tyrosine kinase inhibitors for patients with lung adenocarcinoma harboring different epidermal growth factor receptor …

S Park, SY Lee, D Kim, YS Sim, JS Ryu, J Choi, SH Lee… - BMC cancer, 2021 - Springer
… ) mutations in nonsmall-cell lung cancer predict sensitivity to … and compare the treatment
efficacy of afatinib, erlotinib, and … first-line treatment, and 10 (2.8%) received them as third-line

Osimertinib versus comparator EGFR TKI as first-line treatment for EGFR-mutated advanced NSCLC: FLAURA China, a randomized study

Y Cheng, Y He, W Li, H Zhang, Q Zhou, B Wang… - Targeted Oncology, 2021 - Springer
… ) mutations in patients with non-small-cell lung cancer (NSCLC) is … Here, we report efficacy
and safety data from the FLAURA … 2L second line, 3L third line, EGFR epidermal growth factor …

[HTML][HTML] New data highlighting the efficacy and safety outcomes of third‐generation EGFR‐TKI in NSCLC patients with rare EGFR mutations

W Zhang, F Li, W Gao - Thoracic Cancer, 2020 - ncbi.nlm.nih.gov
… 85% of lung cancers are nonsmallcell lung cancer (NSCLC… EGFR‐TKIs, such as gefitinib,
erlotinib, afatinib, dacomitinib, … receiving second‐ and thirdline osimertinib therapy. In my …

Comparative efficacy of second-and subsequent-line treatments for metastatic NSCLC: a fractional polynomials network meta-analysis of cancer immunotherapies

C Schulz, D Gandara, CG Berardo, R Rosenthal… - Clinical Lung Cancer, 2019 - Elsevier
… NMA for some treatment comparisons within closed loops, namely erlotinib 150 mg, …
advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy

[HTML][HTML] Anlotinib combined with gefitinib can significantly improve the proliferation of epidermal growth factor receptor-mutant advanced non-small cell lung cancer in …

T Li, Y Qian, C Zhang, J Uchino… - … Lung Cancer …, 2021 - ncbi.nlm.nih.gov
… clinical use in China include gefitinib, erlotinib, and icotinib (5… Anlotinib has been recommended
as a third-line treatment for … In view of the difference in efficacy among patients in this …