Remembering the canonical discoverers of the core components of the mammalian cardiac conduction system: Keith and Flack, Aschoff and Tawara, His, and Purkinje
I Cavero, H Holzgrefe - Advances in Physiology Education, 2022 - journals.physiology.org
… Keith emphasized competitive factors. However, … oscillator emitting cyclic SDD events of
variable slopes via the intervention of autonomic transmitters, now denoted as the I f pacemaker …
variable slopes via the intervention of autonomic transmitters, now denoted as the I f pacemaker …
Signatures of the autonomic nervous system and the heart's pacemaker cells in canine electrocardiograms and their applications to humans
AA Rosenberg, I Weiser-Bitoun, GE Billman… - Scientific Reports, 2020 - nature.com
… into how changes in the SAN’s coupled clock system can affect the SAN features present
in the beat intervals, we used a mathematical model consisting of two mechanical oscillators (…
in the beat intervals, we used a mathematical model consisting of two mechanical oscillators (…
Competition between desired competitive result, tolerable homeostatic disturbance, and psychophysiological interpretation determines pacing strategy
C Foster, JJ De Koning… - … journal of sports …, 2023 - journals.humankinetics.com
… proposing a continuous oscillation between psychological drives (eg, competitive goals) and
… historical races for that athlete). Bottom: Progressive depletion of D′ to near zero values in …
… historical races for that athlete). Bottom: Progressive depletion of D′ to near zero values in …
A bioelectrical phase transition patterns the first vertebrate heartbeats
… In the mature heart, this function is driven by an anatomically localized pacemaker. By …
punctuated by occasional jumps suggests competition among many cellular oscillators, each with …
punctuated by occasional jumps suggests competition among many cellular oscillators, each with …
A dual-clock-driven model of lymphatic muscle cell pacemaking to emulate knock-out of Ano1 or IP3R
… the key mechanisms and system effects that drive pacemaking in LMCs. To achieve this
goal, we have focused on determining the underlying oscillators in a single LMC 10 and how …
goal, we have focused on determining the underlying oscillators in a single LMC 10 and how …
Assembly of the cardiac pacemaking complex: electrogenic principles of sinoatrial node morphogenesis
M Easterling, S Rossi, AJ Mazzella… - Journal of Cardiovascular …, 2021 - mdpi.com
… At low levels of coupling, pacemaker cells display independent oscillation. As coupling is
progressively increased: (1) dynamic patterns of entrainment with varying frequency emerge, (2…
progressively increased: (1) dynamic patterns of entrainment with varying frequency emerge, (2…
The surprising heart revisited: an early history of the funny current with modern lessons
D Noble - Progress in Biophysics and Molecular Biology, 2021 - Elsevier
… rhythm generation in the heart. It did so by turning a theory of pacemaker activity upside down.
… pacemaker depolarization to the slow activation of a channel conducting sodium ions into …
… pacemaker depolarization to the slow activation of a channel conducting sodium ions into …
Uncertainty analysis of heart dynamics using Random Matrix Theory
… Van der Pol oscillators, representing the behavior of the two cardiac pacemakers, SA and
AV … The authors declare that they have no known competing financial interests or personal …
AV … The authors declare that they have no known competing financial interests or personal …
Respiratory–cardiovascular interactions
… and cardiovascular systems contain numerous oscillators, and … the first historic representation
of blood pressure and heart rate … Conflicting results were obtained since the introduction of …
of blood pressure and heart rate … Conflicting results were obtained since the introduction of …
Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling
L Guarina, AN Moghbel… - Journal of General …, 2022 - rupress.org
… A salient feature of healthy cardiac function is the reliable and precise beat-to-beat pacemaking
and amplitude of Ca 2+ transients during EC coupling. In this review, we discuss recent …
and amplitude of Ca 2+ transients during EC coupling. In this review, we discuss recent …