The virtual sinoatrial node: What did computational models tell us about cardiac pacemaking?
E Ricci, C Bartolucci, S Severi - Progress in Biophysics and Molecular …, 2023 - Elsevier
… Experiments often produced conflicting … This review presents the most updated SAN
computational models and discusses their contribution to our understanding of cardiac pacemaking. …
computational models and discusses their contribution to our understanding of cardiac pacemaking. …
[HTML][HTML] Focus: Clocks and cycles: Peripheral circadian oscillators
AJ Brown, JS Pendergast… - The Yale journal of biology …, 2019 - ncbi.nlm.nih.gov
… of master pacemaker(s) in the brain and oscillators in peripheral … restricted feeding provided
two conflicting environmental cues, … for sharing his collection of historical literature. We also …
two conflicting environmental cues, … for sharing his collection of historical literature. We also …
[HTML][HTML] Respiratory rhythm generation and pattern formation: oscillators and network mechanisms
MGZ Ghali - Journal of Integrative Neuroscience, 2019 - imrpress.com
… by the interaction of oscillators disparately distributed … predicated upon pacemaker, network,
or hybrid pacemaker network … and extrapolations of the conflicting data predicated upon …
or hybrid pacemaker network … and extrapolations of the conflicting data predicated upon …
What makes the sinoatrial node tick? A question not for the faint of heart
L Donald, EG Lakatta - Philosophical Transactions of the …, 2023 - royalsocietypublishing.org
… of pacemaker electrophysiology and cardiac contractility … of knowledge over the past few
decades regarding how local … Prior to the appreciation of how a coupled-oscillator system …
decades regarding how local … Prior to the appreciation of how a coupled-oscillator system …
Dual activation of phosphodiesterase 3 and 4 regulates basal cardiac pacemaker function and beyond
TM Vinogradova, EG Lakatta - International journal of molecular sciences, 2021 - mdpi.com
… The aim of this review is to highlight one of the essential intrinsic mechanisms, ie, … cardiac
pacemaker function. Here, we first provide a brief overview of the “coupled-clock” pacemaker …
pacemaker function. Here, we first provide a brief overview of the “coupled-clock” pacemaker …
Signatures of the autonomic nervous system and the heart's pacemaker cells in canine electrocardiograms and their applications to humans
AA Rosenberg, I Weiser-Bitoun, GE Billman… - Scientific Reports, 2020 - nature.com
… into how changes in the SAN’s coupled clock system can affect the SAN features present
in the beat intervals, we used a mathematical model consisting of two mechanical oscillators (…
in the beat intervals, we used a mathematical model consisting of two mechanical oscillators (…
Cardiac pacemaker activity and aging
… pacemaker cells along with structural remodeling and a blunted β-adrenergic response. In
this review, … reduction in pacemaker activity with age and highlight key areas for future work. …
this review, … reduction in pacemaker activity with age and highlight key areas for future work. …
Respiratory–cardiovascular interactions
… and cardiovascular systems contain numerous oscillators, and … the first historic representation
of blood pressure and heart rate … Conflicting results were obtained since the introduction of …
of blood pressure and heart rate … Conflicting results were obtained since the introduction of …
Using mathematics to diagnose, cure, and predict cardiac arrhythmia
L Glass - Chaos: An Interdisciplinary Journal of Nonlinear …, 2020 - pubs.aip.org
… Over the past 40 years, there have been major advances in … of periodically forced cardiac
oscillators. Subsequently, … an independent ventricular pacemaker that competes with the sinus …
oscillators. Subsequently, … an independent ventricular pacemaker that competes with the sinus …