Comprehensive genomic review of TCGA head and neck squamous cell carcinomas (HNSCC)

M Perez Sayans, CM Chamorro Petronacci… - Journal of clinical …, 2019 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) encompass a heterogeneous
group of malignancies that begin in the upper aerodigestive tract mucosae. HNSCCs …

… and neck squamous cell carcinoma: associations between radiomic phenotypes and genomic mechanisms via integration of the cancer genome atlas and the cancer …

Y Zhu, ASR Mohamed, SY Lai, S Yang… - JCO clinical cancer …, 2019 - ascopubs.org
… a comprehensive study to discover the imaginggenomic associations in head and neck
squamous cell carcinoma (HNSCC) and explore the potential of predicting tumor genomic

A genome-wide association study identifies two novel susceptible regions for squamous cell carcinoma of the head and neck

S Shete, H Liu, J Wang, R Yu, EM Sturgis, G Li… - Cancer research, 2020 - AACR
… To identify genetic variants for risk of squamous cell carcinoma of the head and neck (SCCHN),
we conducted a two-phase genome-wide association study consisting of 7,858,089 …

[HTML][HTML] Comprehensive characterization of the alternative splicing landscape in head and neck squamous cell carcinoma reveals novel events associated with …

ZX Li, ZQ Zheng, ZH Wei, LL Zhang, F Li, L Lin… - Theranostics, 2019 - ncbi.nlm.nih.gov
… Conclusion: This comprehensive genome-wide analysis of the AS landscape in HNSC
revealed novel AS events related to carcinogenesis and immune microenvironment, with …

Integrated genomic and functional microRNA analysis identifies miR-30-5p as a tumor suppressor and potential therapeutic nanomedicine in head and neck cancer

AD Saleh, H Cheng, SE Martin, H Si, P Ormanoglu… - Clinical Cancer …, 2019 - AACR
… Deregulation of mRNAs and miRNAs has been observed in head and neck squamous cell
carcinomas (HNSCC; ref. 3). Insights gained through genome-wide analyses have uncovered …

Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
… The search for biomarkers has focused on defining the molecular abnormalities that
characterize HNSCC. In this section, we highlight findings regarding genetic and epigenetic …

Comprehensive immunogenomic landscape analysis of prognosis-related genes in head and neck cancer

L Li, XL Wang, Q Lei, CZ Sun, Y Xi, R Chen, YW He - Scientific reports, 2020 - nature.com
… to identify prognostic biomarkers for head and neck squamous cell carcinoma (HNSCC). …
characteristics by interrogating RNA-seq data from 527 HNSCC patients in the cancer genome

Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma

C Huang, L Chen, SR Savage, RV Eguez, Y Dou, Y Li… - Cancer cell, 2021 - cell.com
We present a proteogenomic study of 108 human papilloma virus (HPV)-negative head and
neck squamous cell carcinomas (HNSCCs). Proteomic analysis systematically catalogs …

Translational genomics and recent advances in oral squamous cell carcinoma

AWY Chai, KP Lim, SC Cheong - Seminars in cancer biology, 2020 - Elsevier
… to non-OSCC head and neck cancers and other squamous cell carcinomas, and HRAS and
… of cancers including OSCC, genomics studies also dissected the genetic signatures of the …

Cancer stem cells in head and neck squamous cell carcinoma: identification, characterization and clinical implications

C Peitzsch, J Nathansen, SI Schniewind, F Schwarz… - Cancers, 2019 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth most commonly diagnosed
cancer worldwide. Despite advances in the treatment management, locally advanced …