Drug therapies and delivery mechanisms to treat perturbed skin wound healing

JS Chin, L Madden, SY Chew, DL Becker - Advanced Drug Delivery …, 2019 - Elsevier
cell migration as well as enhancing proliferation of vascular … Keratinocyte proliferation and
migration were encouraged … opening of connexons during tissue injury, short peptides that …

Intercellular Communication in Airway Epithelial Cell Regeneration: Potential Roles of Connexins and Pannexins

M Badaoui, M Chanson - International Journal of Molecular Sciences, 2023 - mdpi.com
… has been observed in keratinocytes from klf4-deficient mice … KLF4 mRNA levels in human
airway epithelial cell lines [56,… of cell migration in repairing human airway epithelial cells led …

Connexin43 hemichannel targeting with TAT-Gap19 alleviates radiation-induced endothelial cell damage

R Ramadan, E Vromans, DC Anang… - Frontiers in …, 2020 - frontiersin.org
connexin proteins (Cxs), ie Gap junctions (direct cell-cell … indicated a significant increase
of 7.4% in the rates of major … this peptide significantly reduced oxidative stress, cell death, …

[图书][B] Mathematical modelling for topographically influenced cell migration and the modulating effect of Gap27 on connexin 43 cycling and 2-d scrape wound closure …

AJ Mitchinson - 2022 - search.proquest.com
keratinocytes, activated endothelial cells are stimulated to … 3-d skin models, in vivo animal
models and ex vivo human skin [… connexin-based channel activity increased migration rates in …

Wound healing of the corneal epithelium: A review

N Abd Ghafar, NAA Jalil, TA Kamarudin - Asian Biomedicine, 2021 - sciendo.com
… The cells migrate at a constant rate of 0.05–0.06 mm/h and do not … and keratinocyte growth
factor on corneal epithelial cell cycle … Effect of connexin 43 inhibition by the mimetic peptide

The regulation of Pannexin1 and Pannexin2 in the skin in health and disease

RE Sanchez Pupo - 2021 - ir.lib.uwo.ca
keratinocyte death after UVB, which may contribute to skin … mouse skin regardless of age,
and its levels increase during … Pannexins share homology with innexins but not connexins, …

[PDF][PDF] The role of Cx43‐mediated signalling in diabetic and non diabetic wound healing events

P Martin - mmsg.mathmos.net
… in the wound bed including cell migration rates, deposition of … Two 2D and 3D cultures of
keratinocytes and fibroblasts will … connexin signalling and adhesion events on cell migration

The Regulation of Pannexin1 and Pannexin2 in the Skin in Health and Disease

RES Pupo - 2021 - search.proquest.com
keratinocyte death after UVB, which may contribute to skin … mouse skin regardless of age,
and its levels increase during … Pannexins share homology with innexins but not connexins, …

Connexins in cancer: Jekyll or Hyde?

EE Mulkearns-Hubert, O Reizes, JD Lathia - Biomolecules, 2020 - mdpi.com
cells have been shown to express low levels of all connexins … the invasion of transformed
keratinocytes in a GJIC-… N-cadherin expression and drives collective cell migration [198]. As for …

[Retracted] Fibroblasts in Scar Formation: Biology and Clinical Translation

H Qian, Y Shan, R Gong, D Lin, M Zhang… - Oxidative Medicine …, 2022 - Wiley Online Library
… Many situations can cause skin injuries, and most human skin … The significant upregulation
of Connexin 43 (Cx43) in … , promoting filopodia formation and cell migration. Blockade of this …