… The Surviving Sepsis Campaign has weakly recommended … continuous intravenous
infusion) or an intermittent β-lactam … of any single study, indicating that the meta-analysis was …

… , the latest Surviving Sepsis Campaign guidelines suggest a “… In a meta-analysis of individual
patient data from RCTs, it … favor prolonged infusion strategies given the ongoing possibility …

… management of sepsis and septic shock (Surviving Sepsis Campaign… of β-lactam antibiotics
administered via continuous infusion or … The individual characteristics of trials included in the …

… Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual
… Campaign: international guidelines for management of severe sepsis and septic shock: …

… (2) the continuous infusion versus intermittent administration of MERopenem in … meta-analysis
to assess whether in critically ill patients with sepsis or septic shock, a prolonged infusion …

… severe sepsis, it was found that the administration of β-lactam antibiotics via continuous
infusion … studies, we conducted cumulative meta-analysis, which revealed that no single study …

… in this meta-analysis.The … individual RCTs have not been able to demonstrate a
significant improvement of clinical outcome in sepsis in the ICU with the use of continuous β-lactam …

… during continuous renal replacement therapy, inter-individual … both extended and continuous
infusion strategies and thus the … A recent meta-analysis (based on 13 RCTs) of II β-lactam …

… Extended infusions, especially continuous infusion of β-lactam … with severe sepsis and
pneumonia, and meta-analysis … A random effect model was employed to pool individual ORs; …

… administration of meropenem in patients with severe sepsis and septic shock: A prospective
… randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis. …