The obese adipose tissue microenvironment in cancer development and progression

DF Quail, AJ Dannenberg - Nature Reviews Endocrinology, 2019 - nature.com
… tumour types, and is estimated to contribute to up to 20% of cancer-related deaths. These …
changes in adipose tissue that disrupt physiological homeostasis both within local tissues and …

The importance of breast adipose tissue in breast cancer

C Kothari, C Diorio, F Durocher - International journal of molecular …, 2020 - mdpi.com
… cells of the breast including adipose tissue. In this review, we will discuss the importance
of the breast adipose tissue ”organ” in breast development through puberty, pregnancy and …

The role of adipose tissue in cardiovascular health and disease

EK Oikonomou, C Antoniades - Nature Reviews Cardiology, 2019 - nature.com
… of the adipose tissue has led to a major shift in our understanding of its role in health and
disease. The … In addition, we highlight the latest developments in adipose tissue imaging for …

Cancer-associated adipocytes: key players in breast cancer progression

Q Wu, B Li, Z Li, J Li, S Sun, S Sun - Journal of hematology & oncology, 2019 - Springer
… in adipose mass and an alteration of adipose tissue, is … be an independent risk factor for
cancer progression. In this review… the importance of CAAs in the biological features of tumor cells …

Diabetes mellitus and its metabolic complications: the role of adipose tissues

L Dilworth, A Facey, F Omoruyi - International journal of molecular …, 2021 - mdpi.com
… This review will highlight the role of adipose tissue in the pathogenesis of diabetes and
the … Among the pro-inflammatory cytokines, tumor necrosis factor-alpha is one of the most …

Contribution of adipogenesis to healthy adipose tissue expansion in obesity

L Vishvanath, RK Gupta - The Journal of clinical …, 2019 - Am Soc Clin Investig
… The importance of these cells in controlling adipose tissue hyperplasia under physiological
conditions still needs to be evaluated. Moreover, it is of interest to determine whether such …

Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome

CR Kahn, G Wang, KY Lee - The Journal of clinical …, 2019 - Am Soc Clin Investig
adipose tissue biology and its role in metabolism. This includes new insights into the multiple
layers of adipose tissue … also been linked to some cancers, including breast cancer (100), …

Innate immune control of adipose tissue homeostasis

H Kane, L Lynch - Trends in immunology, 2019 - cell.com
role in adipose tissue remodeling and thermogenesis. We discuss how the protective capacity
of the adipose … present in adipose tissue and discuss their role in both lean and obese …

Tissue immune cells fuel obesity-associated inflammation in adipose tissue and beyond

R Liu, BS Nikolajczyk - Frontiers in immunology, 2019 - frontiersin.org
… Herein we discuss functions of adaptive immune cell subsets in AT, liver and intestine
during obesity and obesity-associated cancers, with additional focus on the importance of …

The endocrine function of adipose tissues in health and cardiometabolic disease

L Scheja, J Heeren - Nature reviews endocrinology, 2019 - nature.com
adipose tissues a challenge. In this Review, we discuss the functional role of adipose tissue-…
we highlight how these factors contribute to the development of cardiometabolic diseases. …