[PDF][PDF] Nanotechnology approaches for enhanced CNS drug delivery in the management of Schizophrenia Rajalakshmi Rajendran1, Krishnakumar Neelakandha …

C Nair - apb.tbzmed.ac.ir
… GABA receptor positive allosteric modulators … method that facilitate drug transport using
liposomes and other carriers.… Metabotropic glutamate receptor is involved in the pathophysiology …

[HTML][HTML] Pharmacology of adenosine receptors: Recent advancements

F Vincenzi, S Pasquini, C Contri, M Cappello, M Nigro… - Biomolecules, 2023 - mdpi.com
… Selective A 1 AR agonists or positive allosteric modulators (… , enhancing NMDA receptor
function and increasing glutamate … in vivo after administering the liposome-associated A 2A AR …

Intervention of neuroinflammation in the traumatic brain injury trajectory: In vivo and clinical approaches

NK Prabhakar, H Khan, AK Grewal, TG Singh - International …, 2022 - Elsevier
… We focus on the ability of soluble and cellular inflammatory … Studies showed that NMDA
receptors are mechanosensitive … and spatial control of chemokines and their receptors in TBI. …

Recent development in biodegradable nanovehicle delivery system-assisted immunotherapy

Z Wen, F Liu, Q Chen, Y Xu, H Li, S Sun - Biomaterials science, 2019 - pubs.rsc.org
… , a positive allosteric modulator of metabotropic glutamate … : controlled delivery of a glutamate
receptor enhancer to alter … stable liposomes with pH-sensitive polymers to deliver adjuvants…

Study of expression and role of Metabotropic Glutamate Receptors in Human Acute Myeloid Leukemia cell lines and involvement of L1-CAM in migration of mGluR1+ …

SV BOCCADAMO POMPILI - 2023 - iris.uniroma1.it
… may be under partial control of RE1/REST and that, in the … tissues during acute and chronic
inflammation had a metabolic … allosteric modulator; this allosteric modulator could increase (…

Mechanisms of autoimmune encephalitis

C Papi, C Milano, M Spatola - Current Opinion in Neurology, 2024 - journals.lww.com
… The NMDAR is an ionotropic glutamate receptor comprised of … A positive allosteric modulator
of AMPAR improved the … purified GluN1/GluN2B NMDAR embedded in liposomes, resulting …

[HTML][HTML] Ligand-Gated Ion Channels: Prognostic and Therapeutic Implications for Gliomas

G Hey, R Rao, A Carter, A Reddy, D Valle… - Journal of Personalized …, 2023 - mdpi.com
… P2X purinergic receptor and several glutamate receptors play … Inflammatory responses and
unregulated inflammation have … In glioma, liposomes have been shown to effectively deliver

[HTML][HTML] Molecular mechanisms in the genesis of seizures and epilepsy associated with viral infection

W Löscher, CL Howe - Frontiers in molecular neuroscience, 2022 - frontiersin.org
… The T cell-mediated autoimmune demyelinating disease in SJL … liposome-treated mice
exhibited seizures than liposome … The role of glutamate receptors and transporters in the TMEV …

[HTML][HTML] The immune system and metabolic products in epilepsy and glioma-associated epilepsy: emerging therapeutic directions

S Tripathi, CL Nathan, MC Tate, CM Horbinski… - JCI insight, 2024 - ncbi.nlm.nih.gov
… Current treatment options focus on symptomatic control of … and autoimmune encephalitis (eg,
NMDA receptor encephalitis). … through the release of inflammatory cytokines and glutamate; …

[HTML][HTML] Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update

R Siracusa, RD Paola, S Cuzzocrea… - International journal of …, 2021 - mdpi.com
… data provide evidence that NMDA glutamate receptors in the … site through a local
injection of clodronate liposomes is … that autoimmunity potentially contributes to sub-inflammatory