[HTML][HTML] A new platform for autoimmune diseases. Inducing tolerance with liposomes encapsulating autoantigens

L Almenara-Fuentes, S Rodriguez-Fernandez… - … , Biology and Medicine, 2023 - Elsevier
… Here, we show that PS-liposomes can be adapted to other autoimmuneliposomes without
PS are being used to deliver anti-inflammatory drugs to control autoimmune inflammation

Nanoparticle-neutrophils interactions for autoimmune regulation

D Kupor, ML Felder, S Kodikalla, X Chu… - Advanced Drug Delivery …, 2024 - Elsevier
… in inflammation can provide a means to effectively control their … , such as those found in
autoimmune diseases.Table 1.. … LNPs) and liposomes are established drug delivery vehicles with …

[HTML][HTML] Nanoparticle-based drug delivery systems for induction of tolerance and treatment of autoimmune diseases

H Li, YG Yang, T Sun - Frontiers in bioengineering and biotechnology, 2022 - frontiersin.org
Autoimmune disease is a chronic inflammatory disease … While the activation status of the
DCs controls the induction … corticosteroids, the liposomal drug delivery system effectively …

Autoimmune receptor encephalitis in mice induced by active immunization with conformationally stabilized holoreceptors

BE Jones, KR Tovar, A Goehring… - Science translational …, 2019 - science.org
… Our results provide evidence for neuroinflammation and … Littermate controls (liposome or
saline) of both sexes were … may be of value to study fulminant brain inflammation, we are not yet …

Drug delivery systems as immunomodulators for therapy of infectious disease: Relevance to COVID-19

D Brain, A Plant-Hately, B Heaton, U Arshad… - Advanced Drug Delivery …, 2021 - Elsevier
… and adults will help to prevent and treat infection, and control inflammation and damage. …
type 1 interferon pathway is associated with autoimmune/inflammatory conditions, such as SLE, …

Drug delivery carriers with therapeutic functions

SS Cai, T Li, T Akinade, Y Zhu, KW Leong - Advanced drug delivery reviews, 2021 - Elsevier
… The nanoparticles achieved controlled release of RNase A upon exposure to oxidative …
nanocarriers for the treatment of autoimmune disease and inflammatory conditions. First, we will …

Biomaterial strategies for selective immune tolerance: advances and gaps

ST Carey, C Bridgeman, CM Jewell - Advanced Science, 2023 - Wiley Online Library
… [ 32, 33 ] In models of autoimmunity, delivering these drugs … loaded into liposomes that
provide controlled release of drug … T cells—during active autoimmune inflammation, the authors …

[HTML][HTML] Cutting-edge delivery systems and adjuvants in tolerogenic vaccines: A review

C Puricelli, E Boggio, CL Gigliotti, I Stoppa, S Sutti… - Pharmaceutics, 2022 - mdpi.com
… approaches to autoimmune diseases have involved the management of symptomatic … of
inflammatory arthritis, Capini and colleagues showed that an injection of liposomes loaded with …

Strategies to therapeutically modulate cytokine action

WJ Leonard, JX Lin - Nature Reviews Drug Discovery, 2023 - nature.com
… ) and IL-1 can promote inflammation and/or autoimmune disorders. … controlled for potential
therapeutic benefit, including by cytokine engineering. IL-2 was approved by the FDA for use

Metabolic and immunomodulatory control of type 1 diabetes via orally delivered bile-acid-polymer nanocarriers of insulin or rapamycin

JS Lee, P Han, R Chaudhury, S Khan… - Nature Biomedical …, 2021 - nature.com
… Intestinal permeability and bioavailability of salmon calcitonin liposomesmodulation by
the carrier material itself offers significant therapeutic control over pancreatic inflammation