… recurrence and death from prostate cancer [4, 5, 10]. … burden of copy number alteration is
non-linearly associated with risk of clinical progression and death in advanced prostate cancer, …

… with low or intermediate risk of relapse. Several somatic DNA … hazard modelling to predict
biochemical recurrence. … Combinations of specific CNAs, as well as global CNA burden (…

… based model can correctly predict 73% of relapsed cases and 75% … recurrent regions of
genomic loss and gain, and confirmed that the burden of SCNAs (somatic copy number alteration…

… We found a significantly increased burden of CNAs at relapse, with high PGA levels (Fig.
3e)… We then used the copy number profiles to add the recurrent sample to the phylogenetic …

… We detected 15 recurrent CNAs were associated with … c ROC curves for predicting
metastatic-lethal prostate cancer … d ROC curves for predicting metastatic-lethal prostate cancer …

… how a tumor's mutation burden may help predict response to … However, copy number
alterations (CNA) of individual genes … with respect to biochemical relapse following definitive …

… survival time and lower cancer recurrence, while elevated … In this study, we used DEGs
expression to predict the content … relationship between somatic copy number variation (CNV) …

… Bioinformatics analyses of two relapse-associated … , copy number analysis and immune cell
infiltration analysis. … was observed between the burden of CNVs and PCa relapse and death (…

… -number alteration predicts for an inferior survival and clinical outcomes across a range of …
Furthermore, data on the single-cell nature of copy number or LST burden in single tumor cells …

… copy number alterations are commonly present in cancer … novel biomarkers to predict prostate
cancer aggressiveness at … is associated with biochemical recurrence and metastasis. In a …