Advances in non-invasive biomarkers for the diagnosis and monitoring of non-alcoholic fatty liver disease

MT Long, S Gandhi, R Loomba - Metabolism, 2020 - Elsevier
growth factor 21 (FGF21) is a hormone-like growth factor … of liver decompensation, liver
transplantations, and deaths [86]. Baseline liver stiffness measure by SSI correlated with hepatic

EGR1 transcription factor is a multifaceted regulator of matrix production in tendons and other connective tissues

E Havis, D Duprez - International journal of molecular sciences, 2020 - mdpi.com
… Fibroblast deregulation leads to fibrosis, assessed by … laboratories as a rapidly and transiently
activated gene in various … TNMD mRNA expression levels are strongly correlated with the …

Relevance of vitamin D on NAFLD and liver fibrosis detected by vibration controlled transient elastography in US adults: a cross-sectional analysis of NHANES 2017 …

Y Ji, CB Wei, W Gu, LL Hou - Annals of medicine, 2023 - Taylor & Francis
… Significant LF was identified by the liver stiffness measurement value of ≥ 7.9 kPa. … In
consistent with our current conclusion, the negative correlation of vitamin D with LF determined by …

Circulating thrombospondin-2 as a novel fibrosis biomarker of nonalcoholic fatty liver disease in type 2 diabetes

CH Lee, WK Seto, DTW Lui, CHY Fong, HY Wan… - Diabetes …, 2021 - Am Diabetes Assoc
… All participants received vibration-controlled transient … influence on transforming growth
factor-β activity (11,33). … -1, transforming growth factor beta and connective tissue growth factor at …

Mechanobiology of portal hypertension

E Felli, S Selicean, S Guixé-Muntet, C Wang, J Bosch… - JHEP reports, 2023 - Elsevier
… for translocation of transcription factors or co-factors. Yes-… , a higher liver stiffness as measured
by transient elastography is … a positive correlation between ECM stiffness of HCC tissues

[HTML][HTML] Mechano-signaling aspects of hepatocellular carcinoma

M Passi, S Zahler - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
… protein family) and connective tissue growth factor (CTGF). During liver fibrosis, many of …
In some studies, it was found that patients with liver stiffness values of >12.5-13 kPa had a 4 …

[PDF][PDF] Liver fibrosis in nonalcoholic fatty liver disease patients: Noninvasive evaluation and correlation with cardiovascular disease and mortality

S Ballestri, A Mantovani, M Di Girolamo… - Metab Target Organ …, 2023 - f.oaes.cc
… transforming growth factor-β and platelet-derived growth factor… can increase liver stiffness
and elevate the measurements, … between liver fibrosis severity assessed by transient

[HTML][HTML] Increased sinusoidal pressure impairs liver endothelial mechanosensing, uncovering novel biomarkers of portal hypertension

M Ortega-Ribera, A Gibert-Ramos, L Abad-Jordà… - JHEP reports, 2023 - Elsevier
… (CBX7) as a key transcription factor diminished by pressure. … The correlations were calculated
by Pearson’s correlation. … markers of liver fibrosis or PH, including transient elastography, …

Intriguing findings of liver fibrosis following COVID-19

O Kolesova, I Vanaga, S Laivacuma, A Derovs… - BMC …, 2021 - Springer
… FIB-4 may not reflect liver fibrosis due to transient elevation of … Produced by fibroblasts and
specialized connective tissue … FIB-4 and to detect their relationship with liver function tests, …

[HTML][HTML] Nonalcoholic fatty liver disease and portal hypertension

M Ryou, N Stylopoulos, G Baffy - Exploration of medicine, 2020 - ncbi.nlm.nih.gov
… HVPG measurements and transient liver elastography … has been studied to correlate with
hepatic vessel pressures [64]. … of KLF2, a transcription factor responsive to shear stress with …